ROS-responsive adaptive injectable hydrogel promoting inflammatory mastoid bone repair through efficient sterilization and regulating oxidative stress and macrophage phenotype

ROS-responsive adaptive injectable hydrogel promoting inflammatory mastoid bone repair through efficient sterilization and regulating oxidative stress and macrophage phenotype

Chronic suppurative otitis media (CSOM) and middle ear cholesteatoma (MEC) are prevalent disorders in the otology specialty. A major challenge is efficiently eliminating dormant opportunistic infections, controlling inflammation, and repairing defected mastoid portion in the middle ear simultaneousl...

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Bibliographic Details
Main Authors: Yiwen Chen, Ying Lin, Zeyang Liu, Yuanhui Zhang, Ziwei Hu, Maomao Ai, Yanxiong Shen, Dongling Lian, Chenxinwei Wang, Xiaoping Liu, Qunfeng Liu, Huilong Guo, Feng Yu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Otitis media
Defects of mastoid portion
Bone repairment
Macrophage polarization
Tissue microenvironment
Dynamic cross-linked network hydrogels
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425004168
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