A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment
Bladder cancer (BC) remains a clinical challenge due to its complex etiology and high incidence, especially in developed populations. This article presents a broad analysis of the latest advances in BC treatment, offering a new perspective on the growing role of innovative therapies that are effecti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-06-01
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| Series: | Uro |
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| Online Access: | https://www.mdpi.com/2673-4397/5/2/11 |
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| author | Dominik Godlewski Sara Czech Jakub Szpara Dorota Bartusik-Aebisher David Aebisher |
| author_facet | Dominik Godlewski Sara Czech Jakub Szpara Dorota Bartusik-Aebisher David Aebisher |
| author_sort | Dominik Godlewski |
| collection | DOAJ |
| description | Bladder cancer (BC) remains a clinical challenge due to its complex etiology and high incidence, especially in developed populations. This article presents a broad analysis of the latest advances in BC treatment, offering a new perspective on the growing role of innovative therapies that are effectively changing the standards of oncological care. Focusing on targeted therapy, immunotherapy, antibody–drug conjugates, and breakthrough gene therapies, the paper shows how modern approaches can counteract resistance mechanisms and improve treatment efficacy while limiting toxicity for patients. Progress in the field of immune therapies, including checkpoint inhibitors, offers hope for significant improvement in the outcomes of patients with advanced forms of cancer, and the concept of targeted therapy tailored to the molecular characteristics of the tumor indicates the potential of personalized oncology. Gene and photodynamic therapies, in turn, offer new possibilities for precise action on cancer cells, minimizing the side effects of traditional methods. The article presents innovative therapeutic strategies and results of the latest clinical trials, showing the prospects for the development of BC treatment and highlighting the key challenges facing oncology. |
| format | Article |
| id | doaj-art-bdbc3301f63844e4b7cb57a4b59266bc |
| institution | Kabale University |
| issn | 2673-4397 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Uro |
| spelling | doaj-art-bdbc3301f63844e4b7cb57a4b59266bc2025-08-20T03:26:56ZengMDPI AGUro2673-43972025-06-01521110.3390/uro5020011A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer TreatmentDominik Godlewski0Sara Czech1Jakub Szpara2Dorota Bartusik-Aebisher3David Aebisher4Medical Center in Łańcut, 37-100 Łańcut, PolandEnglish Division Science Club, Medical College, The Rzeszów University, 35-959 Rzeszów, PolandEnglish Division Science Club, Medical College, The Rzeszów University, 35-959 Rzeszów, PolandDepartment of Biochemistry and General Chemistry, Medical College, The Rzeszów University, 35-959 Rzeszów, PolandDepartment of Photomedicine and Physical Chemistry, Medical College, The Rzeszów University, 35-959 Rzeszów, PolandBladder cancer (BC) remains a clinical challenge due to its complex etiology and high incidence, especially in developed populations. This article presents a broad analysis of the latest advances in BC treatment, offering a new perspective on the growing role of innovative therapies that are effectively changing the standards of oncological care. Focusing on targeted therapy, immunotherapy, antibody–drug conjugates, and breakthrough gene therapies, the paper shows how modern approaches can counteract resistance mechanisms and improve treatment efficacy while limiting toxicity for patients. Progress in the field of immune therapies, including checkpoint inhibitors, offers hope for significant improvement in the outcomes of patients with advanced forms of cancer, and the concept of targeted therapy tailored to the molecular characteristics of the tumor indicates the potential of personalized oncology. Gene and photodynamic therapies, in turn, offer new possibilities for precise action on cancer cells, minimizing the side effects of traditional methods. The article presents innovative therapeutic strategies and results of the latest clinical trials, showing the prospects for the development of BC treatment and highlighting the key challenges facing oncology.https://www.mdpi.com/2673-4397/5/2/11bladder cancerinnovative treatmentimmunotherapytargeted therapygene therapyantibody–drug conjugates |
| spellingShingle | Dominik Godlewski Sara Czech Jakub Szpara Dorota Bartusik-Aebisher David Aebisher A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment Uro bladder cancer innovative treatment immunotherapy targeted therapy gene therapy antibody–drug conjugates |
| title | A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment |
| title_full | A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment |
| title_fullStr | A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment |
| title_full_unstemmed | A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment |
| title_short | A Narrative Review of Current Advances and Future Changes Regarding Bladder Cancer Treatment |
| title_sort | narrative review of current advances and future changes regarding bladder cancer treatment |
| topic | bladder cancer innovative treatment immunotherapy targeted therapy gene therapy antibody–drug conjugates |
| url | https://www.mdpi.com/2673-4397/5/2/11 |
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