The Contact Allergen Methylisothiazolinone (MIT) is a Potent Activator of the TRPA1 Ion Channel

The Contact Allergen Methylisothiazolinone (MIT) is a Potent Activator of the TRPA1 Ion Channel

ABSTRACT Methylisothiazolinone (MIT) is a known inducer of allergic contact dermatitis that is used as a preservative and a biocide in consumer products. Transient receptor potential ankyrin 1 (TRPA1) is a non‐selective cation channel expressed in neurons and in some nonneuronal cells including kera...

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Main Authors: Ilari Mäki‐Opas, Samu Luostarinen, Mari Hämäläinen, Katsuhiko Muraki, Eeva Moilanen
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Pharmacology Research & Perspectives
Online Access:https://doi.org/10.1002/prp2.70053
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