MiR‐29a/b Suppresses CD8+ T Cell Effector Function and Intestinal Inflammation

MiR‐29a/b Suppresses CD8+ T Cell Effector Function and Intestinal Inflammation

ABSTRACT The role of CD8+ T cells in the pathogenesis of ulcerative colitis (UC) remains unclear. Similarly, the posttranscriptional regulation of the highly heterogenic CD8+ T cell populations and their effector function in IBD also remains poorly understood. Here, we find that miR‐29a and ‐29b (mi...

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Main Authors: Yingying Lin, Yuqi Wang, Yuning Zhang, Yao Lu, Juan Chen, Yongting Luo, Jian He, Qingfeng Luo, Heng Quan, Weiru Yu, Yujia Luo, Peng Xue, Yi Xue, Xiaoya Lin, Rui Ding, Lining Chen, Yiran Wang, Zenghui Xia, Liang Zhao, Hao Zhang, Ran Wang, Qingyu Wang, Xifan Wang, Jiaqi Su, Fazheng Ren, Cong Lv, Yixuan Li, Huiyuan Guo
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Exploration
Subjects:
CD8+ T cell
differentiation
Ifng‐JAK‐STAT
miR‐29a/b
ulcerative colitis
Online Access:https://doi.org/10.1002/EXP.20240363
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