Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep
Prickly ash seeds (PAS), a nutrient-rich by-product, show potential as a sustainable feed for Hu sheep. The current study aims to explore the effects of dietary supplementation with PAS on muscle development and volatile compounds of Hu sheep through multi-omics analysis. The increased muscle fiber...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-12-01
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| Series: | Food Chemistry: Molecular Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666566225000358 |
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| author | Qiao Li Zilong Liu Yi Wu Chunhui Wang Xueyi Ma Youji Ma |
| author_facet | Qiao Li Zilong Liu Yi Wu Chunhui Wang Xueyi Ma Youji Ma |
| author_sort | Qiao Li |
| collection | DOAJ |
| description | Prickly ash seeds (PAS), a nutrient-rich by-product, show potential as a sustainable feed for Hu sheep. The current study aims to explore the effects of dietary supplementation with PAS on muscle development and volatile compounds of Hu sheep through multi-omics analysis. The increased muscle fiber diameter and cross-sectional area was associated with dietary supplementation with PAS compared with the CK group (P < 0.05). Transcriptome analysis showed that ACTC1, SERPINA3, COX2, MYBPH, FMOD, and KLHL34 were key differentially expressed genes (DEGs) involved in muscle growth and development, and played a role through oxidative phosphorylation, TCA cycle, fatty acid metabolism, and tryptophan metabolism. The combined analysis of transcriptome and volatile metabolomics showed that LEP, ADCY1, TMEM54, COX2, PCK1, and CPT1A may play an important regulatory role in the production of volatile compounds such as cetene, dodecanal, 2,6-dodecadien-1-al, palmitoleic acid, dodecanoic acid, ethyl ester by participating in lipid metabolism. In summary, PAS demonstrates promise for Hu sheep production, enhancing muscle development and influencing muscle flavor by modulating fatty acid metabolism-related genes |
| format | Article |
| id | doaj-art-bdaa4bf0ca174d84a85a31145e1e4c10 |
| institution | DOAJ |
| issn | 2666-5662 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: Molecular Sciences |
| spelling | doaj-art-bdaa4bf0ca174d84a85a31145e1e4c102025-08-20T03:12:01ZengElsevierFood Chemistry: Molecular Sciences2666-56622025-12-011110027410.1016/j.fochms.2025.100274Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheepQiao Li0Zilong Liu1Yi Wu2Chunhui Wang3Xueyi Ma4Youji Ma5College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, ChinaCorresponding author.; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, ChinaPrickly ash seeds (PAS), a nutrient-rich by-product, show potential as a sustainable feed for Hu sheep. The current study aims to explore the effects of dietary supplementation with PAS on muscle development and volatile compounds of Hu sheep through multi-omics analysis. The increased muscle fiber diameter and cross-sectional area was associated with dietary supplementation with PAS compared with the CK group (P < 0.05). Transcriptome analysis showed that ACTC1, SERPINA3, COX2, MYBPH, FMOD, and KLHL34 were key differentially expressed genes (DEGs) involved in muscle growth and development, and played a role through oxidative phosphorylation, TCA cycle, fatty acid metabolism, and tryptophan metabolism. The combined analysis of transcriptome and volatile metabolomics showed that LEP, ADCY1, TMEM54, COX2, PCK1, and CPT1A may play an important regulatory role in the production of volatile compounds such as cetene, dodecanal, 2,6-dodecadien-1-al, palmitoleic acid, dodecanoic acid, ethyl ester by participating in lipid metabolism. In summary, PAS demonstrates promise for Hu sheep production, enhancing muscle development and influencing muscle flavor by modulating fatty acid metabolism-related geneshttp://www.sciencedirect.com/science/article/pii/S2666566225000358By-productTranscriptomeLongissimus thoracisMuscle flavorLamb meat |
| spellingShingle | Qiao Li Zilong Liu Yi Wu Chunhui Wang Xueyi Ma Youji Ma Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep Food Chemistry: Molecular Sciences By-product Transcriptome Longissimus thoracis Muscle flavor Lamb meat |
| title | Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep |
| title_full | Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep |
| title_fullStr | Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep |
| title_full_unstemmed | Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep |
| title_short | Effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of Hu sheep |
| title_sort | effects of dietary prickly ash seeds supplementation on muscle development and volatile compounds of hu sheep |
| topic | By-product Transcriptome Longissimus thoracis Muscle flavor Lamb meat |
| url | http://www.sciencedirect.com/science/article/pii/S2666566225000358 |
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