Analysis of ferroptosis-related genes in cerebral ischemic stroke via immune infiltration and single-cell RNA-sequencing

Analysis of ferroptosis-related genes in cerebral ischemic stroke via immune infiltration and single-cell RNA-sequencing

Abstract Ischemic stroke (IS) represents a harmful neurological disorder with limited treatment options. Ferroptosis accounts for the iron-dependent, nonapoptotic cell death pattern, which shows the feature of fatal lipid ROS accumulation. Nonetheless, ferroptosis-related biomarkers for identifying...

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Bibliographic Details
Main Authors: Wei Fan, Jinhua Zheng, Fangchao Jiang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Medical Genomics
Subjects:
Ischemic stroke
Ferroptosis
Immune infiltration
Single-cell RNA-sequencing
Nfe2l2/HO-1 pathway
Online Access:https://doi.org/10.1186/s12920-025-02098-4
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