Characterization of membrane potential dependency of mitochondrial Ca2+ uptake by an improved biophysical model of mitochondrial Ca2+ uniporter.
Mitochondrial Ca(2+) uniporter is the primary influx pathway for Ca(2+) into respiring mitochondria, and hence plays a key role in mitochondrial Ca(2+) homeostasis. Though the mechanism of extra-matrix Ca(2+) dependency of mitochondrial Ca(2+) uptake has been well characterized both experimentally a...
Saved in:
| Main Authors: | Ranjan K Pradhan, Feng Qi, Daniel A Beard, Ranjan K Dash |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-10-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013278&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A minimal model for the mitochondrial rapid mode of Ca²+ uptake mechanism.
by: Jason N Bazil, et al.
Published: (2011-01-01) -
The mitochondrial Ca2+ uniporter MCU is essential for glucose-induced ATP increases in pancreatic β-cells.
by: Andrei I Tarasov, et al.
Published: (2012-01-01) -
Mitochondrial calcium uniporter promotes MSU crystal-induced inflammation through inducing mitochondrial Ca2+ overload and ubiquitination of SIRT5 protein
by: Qingqing Yu, et al.
Published: (2025-08-01) -
The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretion.
by: Iulia I Nita, et al.
Published: (2012-01-01) -
Influence of Tariquidar, an ABC Transporter Inhibitor, on the Ca<sup>2+</sup>-Dependent Mitochondrial Permeability Transition Pore
by: Tatiana A. Fedotcheva, et al.
Published: (2025-06-01)