Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management
Platelet-rich plasma (PRP) promotes the wound-healing process and reduces pain. Cord blood platelet-rich plasma (CB-PRP), which can be easily collected from the umbilical cord and reapplied to a cesarean section wound, has been proposed to have similar effects as PRP. This paper hypothesizes that CB...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/ogi/4155779 |
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| author | Amornrat Thanachaiviwat Sutham Suthaporn Patana Teng-umnuay |
| author_facet | Amornrat Thanachaiviwat Sutham Suthaporn Patana Teng-umnuay |
| author_sort | Amornrat Thanachaiviwat |
| collection | DOAJ |
| description | Platelet-rich plasma (PRP) promotes the wound-healing process and reduces pain. Cord blood platelet-rich plasma (CB-PRP), which can be easily collected from the umbilical cord and reapplied to a cesarean section wound, has been proposed to have similar effects as PRP. This paper hypothesizes that CB-PRB would provide beneficial effects in terms of wound healing and pain reduction in women undergoing cesarean section. This study is a randomized controlled trial involving 52 pregnant women who underwent cesarean sections. Participants were assigned to either the intervention group (n = 26) or the control group (n = 26) at the Obstetrics and Gynecology Clinic of Police General Hospital. Cord blood PRP was applied to the subcutaneous layer and the surgical wound immediately following the cesarean section. The efficacy of wound healing was evaluated using the REEDA scale score on days 1 and 3 postoperatively, and the Vancouver Scar Scale (VSS) was assessed in the 8th week postoperation. The efficacy in reducing pain was measured using a Visual Analog Scale on days 1 and 3 postoperatively. The mean REEDA scale on day 1 (mean ± SD: 1.5 ± 0.2561.5 ± 0.256 in the CB-PRP group and 2.5 ± 0.267 in the control group; p=0.009) and the mean VSS score at the 8th week (mean ± SD: 2.577 ± 2.003 in the CB-PRP group and 6.962 ± 2.441 in the control group; p<0.001) were significantly lower in the CB-PRP group than those in the control group. However, there were no differences in Visual Analog Scale values between the two groups. The findings indicate that CB-PRP potentially promotes wound healing following cesarean sections but does not reduce pain. Further research is needed to confirm the beneficial effects of CB-PRP. |
| format | Article |
| id | doaj-art-bd8ec2b322b346c2b5b6503b19faa4e0 |
| institution | DOAJ |
| issn | 1687-9597 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-bd8ec2b322b346c2b5b6503b19faa4e02025-08-20T02:52:11ZengWileyObstetrics and Gynecology International1687-95972024-01-01202410.1155/ogi/4155779Cord Blood Platelet-Rich Plasma in Cesarean Section Wound ManagementAmornrat Thanachaiviwat0Sutham Suthaporn1Patana Teng-umnuay2Department of Obstetrics and GynaecologyDepartment of Obstetrics and GynaecologyDepartment of Integrative MedicinePlatelet-rich plasma (PRP) promotes the wound-healing process and reduces pain. Cord blood platelet-rich plasma (CB-PRP), which can be easily collected from the umbilical cord and reapplied to a cesarean section wound, has been proposed to have similar effects as PRP. This paper hypothesizes that CB-PRB would provide beneficial effects in terms of wound healing and pain reduction in women undergoing cesarean section. This study is a randomized controlled trial involving 52 pregnant women who underwent cesarean sections. Participants were assigned to either the intervention group (n = 26) or the control group (n = 26) at the Obstetrics and Gynecology Clinic of Police General Hospital. Cord blood PRP was applied to the subcutaneous layer and the surgical wound immediately following the cesarean section. The efficacy of wound healing was evaluated using the REEDA scale score on days 1 and 3 postoperatively, and the Vancouver Scar Scale (VSS) was assessed in the 8th week postoperation. The efficacy in reducing pain was measured using a Visual Analog Scale on days 1 and 3 postoperatively. The mean REEDA scale on day 1 (mean ± SD: 1.5 ± 0.2561.5 ± 0.256 in the CB-PRP group and 2.5 ± 0.267 in the control group; p=0.009) and the mean VSS score at the 8th week (mean ± SD: 2.577 ± 2.003 in the CB-PRP group and 6.962 ± 2.441 in the control group; p<0.001) were significantly lower in the CB-PRP group than those in the control group. However, there were no differences in Visual Analog Scale values between the two groups. The findings indicate that CB-PRP potentially promotes wound healing following cesarean sections but does not reduce pain. Further research is needed to confirm the beneficial effects of CB-PRP.http://dx.doi.org/10.1155/ogi/4155779 |
| spellingShingle | Amornrat Thanachaiviwat Sutham Suthaporn Patana Teng-umnuay Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management Obstetrics and Gynecology International |
| title | Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management |
| title_full | Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management |
| title_fullStr | Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management |
| title_full_unstemmed | Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management |
| title_short | Cord Blood Platelet-Rich Plasma in Cesarean Section Wound Management |
| title_sort | cord blood platelet rich plasma in cesarean section wound management |
| url | http://dx.doi.org/10.1155/ogi/4155779 |
| work_keys_str_mv | AT amornratthanachaiviwat cordbloodplateletrichplasmaincesareansectionwoundmanagement AT suthamsuthaporn cordbloodplateletrichplasmaincesareansectionwoundmanagement AT patanatengumnuay cordbloodplateletrichplasmaincesareansectionwoundmanagement |