Pediatric Endocrine Hypertension Related to the Adrenal Glands
Endocrine causes of pediatric hypertension are relatively rare but important because of their distinct treatment options. Adrenal diseases accompanied by an excess of mineralocorticoids, glucocorticoids, and catecholamines are major causes...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Ewha Womans University College of Medicine
2023-12-01
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| Series: | The Ewha Medical Journal |
| Subjects: | |
| Online Access: | http://www.e-emj.org/archive/view_article?pid=emj-46-s1-30 |
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| Summary: | Endocrine causes of pediatric hypertension are relatively rare but important
because of their distinct treatment options. Adrenal diseases accompanied by an
excess of mineralocorticoids, glucocorticoids, and catecholamines are major
causes of endocrine hypertension. Typical causes of mineralocorticoid-related
hypertension include primary aldosteronism, congenital adrenal hyperplasia
(11β- and 17α-hydroxylase deficiencies), and apparent
mineralocorticoid excess. Cushing syndrome and pheochromocytoma/paraganglioma
are the primary causes of glucocorticoid- and catecholamine-related
hypertension, respectively. This review provides an overview of the diagnostic
evaluations, including hormonal assays and imaging studies, used to identify the
underlying causes of pediatric endocrine hypertension, focusing on adrenal
disorders. It presents details regarding the major adrenal disorders and
recommended therapeutic approaches, emphasizing the importance of early
detection and disease-specific management to prevent cardiovascular and
metabolic complications in affected children. |
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| ISSN: | 2234-2591 |