OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.

Movement is fundamental to human and animal life, emerging through interaction of complex neural, muscular, and skeletal systems. Study of movement draws from and contributes to diverse fields, including biology, neuroscience, mechanics, and robotics. OpenSim unites methods from these fields to crea...

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Main Authors: Ajay Seth, Jennifer L Hicks, Thomas K Uchida, Ayman Habib, Christopher L Dembia, James J Dunne, Carmichael F Ong, Matthew S DeMers, Apoorva Rajagopal, Matthew Millard, Samuel R Hamner, Edith M Arnold, Jennifer R Yong, Shrinidhi K Lakshmikanth, Michael A Sherman, Joy P Ku, Scott L Delp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006223&type=printable
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author Ajay Seth
Jennifer L Hicks
Thomas K Uchida
Ayman Habib
Christopher L Dembia
James J Dunne
Carmichael F Ong
Matthew S DeMers
Apoorva Rajagopal
Matthew Millard
Samuel R Hamner
Edith M Arnold
Jennifer R Yong
Shrinidhi K Lakshmikanth
Michael A Sherman
Joy P Ku
Scott L Delp
author_facet Ajay Seth
Jennifer L Hicks
Thomas K Uchida
Ayman Habib
Christopher L Dembia
James J Dunne
Carmichael F Ong
Matthew S DeMers
Apoorva Rajagopal
Matthew Millard
Samuel R Hamner
Edith M Arnold
Jennifer R Yong
Shrinidhi K Lakshmikanth
Michael A Sherman
Joy P Ku
Scott L Delp
author_sort Ajay Seth
collection DOAJ
description Movement is fundamental to human and animal life, emerging through interaction of complex neural, muscular, and skeletal systems. Study of movement draws from and contributes to diverse fields, including biology, neuroscience, mechanics, and robotics. OpenSim unites methods from these fields to create fast and accurate simulations of movement, enabling two fundamental tasks. First, the software can calculate variables that are difficult to measure experimentally, such as the forces generated by muscles and the stretch and recoil of tendons during movement. Second, OpenSim can predict novel movements from models of motor control, such as kinematic adaptations of human gait during loaded or inclined walking. Changes in musculoskeletal dynamics following surgery or due to human-device interaction can also be simulated; these simulations have played a vital role in several applications, including the design of implantable mechanical devices to improve human grasping in individuals with paralysis. OpenSim is an extensible and user-friendly software package built on decades of knowledge about computational modeling and simulation of biomechanical systems. OpenSim's design enables computational scientists to create new state-of-the-art software tools and empowers others to use these tools in research and clinical applications. OpenSim supports a large and growing community of biomechanics and rehabilitation researchers, facilitating exchange of models and simulations for reproducing and extending discoveries. Examples, tutorials, documentation, and an active user forum support this community. The OpenSim software is covered by the Apache License 2.0, which permits its use for any purpose including both nonprofit and commercial applications. The source code is freely and anonymously accessible on GitHub, where the community is welcomed to make contributions. Platform-specific installers of OpenSim include a GUI and are available on simtk.org.
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spelling doaj-art-bd8a30f818914e27a1e020d1b2a0b5242025-08-20T02:54:49ZengPublic Library of Science (PLoS)PLoS Computational Biology1553-734X1553-73582018-07-01147e100622310.1371/journal.pcbi.1006223OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.Ajay SethJennifer L HicksThomas K UchidaAyman HabibChristopher L DembiaJames J DunneCarmichael F OngMatthew S DeMersApoorva RajagopalMatthew MillardSamuel R HamnerEdith M ArnoldJennifer R YongShrinidhi K LakshmikanthMichael A ShermanJoy P KuScott L DelpMovement is fundamental to human and animal life, emerging through interaction of complex neural, muscular, and skeletal systems. Study of movement draws from and contributes to diverse fields, including biology, neuroscience, mechanics, and robotics. OpenSim unites methods from these fields to create fast and accurate simulations of movement, enabling two fundamental tasks. First, the software can calculate variables that are difficult to measure experimentally, such as the forces generated by muscles and the stretch and recoil of tendons during movement. Second, OpenSim can predict novel movements from models of motor control, such as kinematic adaptations of human gait during loaded or inclined walking. Changes in musculoskeletal dynamics following surgery or due to human-device interaction can also be simulated; these simulations have played a vital role in several applications, including the design of implantable mechanical devices to improve human grasping in individuals with paralysis. OpenSim is an extensible and user-friendly software package built on decades of knowledge about computational modeling and simulation of biomechanical systems. OpenSim's design enables computational scientists to create new state-of-the-art software tools and empowers others to use these tools in research and clinical applications. OpenSim supports a large and growing community of biomechanics and rehabilitation researchers, facilitating exchange of models and simulations for reproducing and extending discoveries. Examples, tutorials, documentation, and an active user forum support this community. The OpenSim software is covered by the Apache License 2.0, which permits its use for any purpose including both nonprofit and commercial applications. The source code is freely and anonymously accessible on GitHub, where the community is welcomed to make contributions. Platform-specific installers of OpenSim include a GUI and are available on simtk.org.https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006223&type=printable
spellingShingle Ajay Seth
Jennifer L Hicks
Thomas K Uchida
Ayman Habib
Christopher L Dembia
James J Dunne
Carmichael F Ong
Matthew S DeMers
Apoorva Rajagopal
Matthew Millard
Samuel R Hamner
Edith M Arnold
Jennifer R Yong
Shrinidhi K Lakshmikanth
Michael A Sherman
Joy P Ku
Scott L Delp
OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.
PLoS Computational Biology
title OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.
title_full OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.
title_fullStr OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.
title_full_unstemmed OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.
title_short OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.
title_sort opensim simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement
url https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006223&type=printable
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