Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis

<i>Background and Objectives</i>: Periodontal regeneration involves techniques intended at restoring the lost supporting tissue around a periodontally weakened tooth. These regenerative methods frequently utilize periosteal grafts to stimulate the evolvement of vital adjacent tissues. Th...

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Main Authors: Swapna A. Mahale, Prasad Dhadse, Sumedha Thosar, Vedant Bhandari, Akhil Patil, Sadatullah Syed, Ranjeet Ajit Bapat, Tanay Chaubal, Sumaiya Zabin Eusufzai, Shahabe Saquib Abullais
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Language:English
Published: MDPI AG 2025-05-01
Series:Medicina
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Online Access:https://www.mdpi.com/1648-9144/61/5/905
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author Swapna A. Mahale
Prasad Dhadse
Sumedha Thosar
Vedant Bhandari
Akhil Patil
Sadatullah Syed
Ranjeet Ajit Bapat
Tanay Chaubal
Sumaiya Zabin Eusufzai
Shahabe Saquib Abullais
author_facet Swapna A. Mahale
Prasad Dhadse
Sumedha Thosar
Vedant Bhandari
Akhil Patil
Sadatullah Syed
Ranjeet Ajit Bapat
Tanay Chaubal
Sumaiya Zabin Eusufzai
Shahabe Saquib Abullais
author_sort Swapna A. Mahale
collection DOAJ
description <i>Background and Objectives</i>: Periodontal regeneration involves techniques intended at restoring the lost supporting tissue around a periodontally weakened tooth. These regenerative methods frequently utilize periosteal grafts to stimulate the evolvement of vital adjacent tissues. This paper intended to evaluate the use of autogenous periosteal grafts in treating grade II furcation defects (Glickman Classification 1953) in patients with chronic periodontitis. <i>Materials and Methods</i>: The databases MEDLINE (via PubMed), Cochrane, EBSCO, and Google Scholar were searched for papers published in English from January 1991 till December 2022. Three individuals examined the reclaimed articles according to the inclusion norms. Randomized controlled trials (RCTs) assessing the efficacy of autogenous periosteal grafts for treating Grade II furcation defects in chronic periodontitis patients were involved. Only four related studies were identified for data extraction, involving 80 patients aged 18 to 52 years. Outcome variables measured included horizontal bone loss (HD), vertical bone loss (VD), pocket depth (PD), clinical attachment level (CAL), bone height (BH), gingival recession (GR), plaque index (PI), and gingival index (GI). Data were examined using RevMan 5.4.1 software. Mean differences and 95% confidence intervals were employed to estimate effect sizes. <i>Results</i>: Both groups showed similar results for reductions in PI, GI, and BOP. However, The periosteal graft also yielded better outcomes for CAL gain, BH, and GR. The meta-analysis showed a significant overall effect of Periosteal Barrier Membrane (PBM) on horizontal and vertical bony change levels, but subgroup differences between unilateral and bilateral applications were not statistically significant due to high heterogeneity. Although the bilateral subgroup demonstrated significant benefits of PBM treatment, the overall findings across the clinical attachment level group remain inconclusive. <i>Conclusion:</i> Current evidence suggests that while PBM may benefit bilateral mandibular sites, and autogenous periosteal grafts offer no added advantage over OFD alone in Grade II furcation defects, the overall findings remain inconclusive.
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spelling doaj-art-bd7b4a6ef88343c8a1b74f12e620aaf02025-08-20T03:14:43ZengMDPI AGMedicina1010-660X1648-91442025-05-0161590510.3390/medicina61050905Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-AnalysisSwapna A. Mahale0Prasad Dhadse1Sumedha Thosar2Vedant Bhandari3Akhil Patil4Sadatullah Syed5Ranjeet Ajit Bapat6Tanay Chaubal7Sumaiya Zabin Eusufzai8Shahabe Saquib Abullais9Department of Periodontology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha 442001, IndiaDepartment of Periodontology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha 442001, IndiaDepartment of Periodontology, MGV’s KBH Dental College and Hospital, Nashik 422003, IndiaDepartment of Periodontology, MGV’s KBH Dental College and Hospital, Nashik 422003, IndiaDepartment of Periodontology, MGV’s KBH Dental College and Hospital, Nashik 422003, IndiaDepartment of Diagnostic Sciences and Department of Dental Education, College of Dentistry, King Khalid University, Abha 62521, Saudi ArabiaRestorative Dentistry Division, School of Dentistry, IMU University, Kuala Lumpur 57000, MalaysiaCollege of Dentistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USASchool of Dental Sciences, Universiti Sains Malaysia, Kota Bharu 16150, MalaysiaDepartment of Periodontics and Community Dental Science, College of Dentistry, King Khalid University, Abha 62521, Saudi Arabia<i>Background and Objectives</i>: Periodontal regeneration involves techniques intended at restoring the lost supporting tissue around a periodontally weakened tooth. These regenerative methods frequently utilize periosteal grafts to stimulate the evolvement of vital adjacent tissues. This paper intended to evaluate the use of autogenous periosteal grafts in treating grade II furcation defects (Glickman Classification 1953) in patients with chronic periodontitis. <i>Materials and Methods</i>: The databases MEDLINE (via PubMed), Cochrane, EBSCO, and Google Scholar were searched for papers published in English from January 1991 till December 2022. Three individuals examined the reclaimed articles according to the inclusion norms. Randomized controlled trials (RCTs) assessing the efficacy of autogenous periosteal grafts for treating Grade II furcation defects in chronic periodontitis patients were involved. Only four related studies were identified for data extraction, involving 80 patients aged 18 to 52 years. Outcome variables measured included horizontal bone loss (HD), vertical bone loss (VD), pocket depth (PD), clinical attachment level (CAL), bone height (BH), gingival recession (GR), plaque index (PI), and gingival index (GI). Data were examined using RevMan 5.4.1 software. Mean differences and 95% confidence intervals were employed to estimate effect sizes. <i>Results</i>: Both groups showed similar results for reductions in PI, GI, and BOP. However, The periosteal graft also yielded better outcomes for CAL gain, BH, and GR. The meta-analysis showed a significant overall effect of Periosteal Barrier Membrane (PBM) on horizontal and vertical bony change levels, but subgroup differences between unilateral and bilateral applications were not statistically significant due to high heterogeneity. Although the bilateral subgroup demonstrated significant benefits of PBM treatment, the overall findings across the clinical attachment level group remain inconclusive. <i>Conclusion:</i> Current evidence suggests that while PBM may benefit bilateral mandibular sites, and autogenous periosteal grafts offer no added advantage over OFD alone in Grade II furcation defects, the overall findings remain inconclusive.https://www.mdpi.com/1648-9144/61/5/905grade II furcation defectopen flap debridementautogenous periosteal graftmeta-analysissystematic review
spellingShingle Swapna A. Mahale
Prasad Dhadse
Sumedha Thosar
Vedant Bhandari
Akhil Patil
Sadatullah Syed
Ranjeet Ajit Bapat
Tanay Chaubal
Sumaiya Zabin Eusufzai
Shahabe Saquib Abullais
Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis
Medicina
grade II furcation defect
open flap debridement
autogenous periosteal graft
meta-analysis
systematic review
title Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis
title_full Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis
title_fullStr Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis
title_full_unstemmed Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis
title_short Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis
title_sort autogenous periosteal graft along with open flap debridement versus open flap debridement alone for the treatment of grade ii furcation defect in chronic periodontitis patients a systematic review and meta analysis
topic grade II furcation defect
open flap debridement
autogenous periosteal graft
meta-analysis
systematic review
url https://www.mdpi.com/1648-9144/61/5/905
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