Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies
Although schizophrenia is primarily considered to be a neurodevelopmental disorder, there is a growing consensus that the disorder may also involve neurodegeneration. Recent research using non-invasive neuroimaging techniques, such as magnetic resonance imaging, suggests that some patients with schi...
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2007.47 |
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| _version_ | 1850176704264273920 |
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| author | John G. Csernansky |
| author_facet | John G. Csernansky |
| author_sort | John G. Csernansky |
| collection | DOAJ |
| description | Although schizophrenia is primarily considered to be a neurodevelopmental disorder, there is a growing consensus that the disorder may also involve neurodegeneration. Recent research using non-invasive neuroimaging techniques, such as magnetic resonance imaging, suggests that some patients with schizophrenia show progressive losses of gray matter in the frontal and temporal lobes of the brain. The cellular mechanisms responsible for such gray matter losses are unknown, but have been hypothesized to involve abnormal increases in apoptosis. |
| format | Article |
| id | doaj-art-bd7036301bc747b0a5dfbd891477282b |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-bd7036301bc747b0a5dfbd891477282b2025-08-20T02:19:12ZengWileyThe Scientific World Journal1537-744X2007-01-01713514310.1100/tsw.2007.47Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging StudiesJohn G. Csernansky0Departments of Psychiatry and Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO 63110, USAAlthough schizophrenia is primarily considered to be a neurodevelopmental disorder, there is a growing consensus that the disorder may also involve neurodegeneration. Recent research using non-invasive neuroimaging techniques, such as magnetic resonance imaging, suggests that some patients with schizophrenia show progressive losses of gray matter in the frontal and temporal lobes of the brain. The cellular mechanisms responsible for such gray matter losses are unknown, but have been hypothesized to involve abnormal increases in apoptosis.http://dx.doi.org/10.1100/tsw.2007.47 |
| spellingShingle | John G. Csernansky Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies The Scientific World Journal |
| title | Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies |
| title_full | Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies |
| title_fullStr | Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies |
| title_full_unstemmed | Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies |
| title_short | Neurodegeneration in Schizophrenia: Evidence from In Vivo Neuroimaging Studies |
| title_sort | neurodegeneration in schizophrenia evidence from in vivo neuroimaging studies |
| url | http://dx.doi.org/10.1100/tsw.2007.47 |
| work_keys_str_mv | AT johngcsernansky neurodegenerationinschizophreniaevidencefrominvivoneuroimagingstudies |