The clinical observation of human papillomavirus positive breast tumor
In this manuscript, a unique case of HPV16-positive breast cancer is examined. The presence of HPV infection in the tumor is confirmed by two independent methods (PCR and immunohistochemistry). It is shown that in the presence of adverse factors of prognosis (lymphogenous metastasis, high level of K...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2018-03-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1133 |
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| author | M. K. Ibragimova M. M. Tsyganov N. A. Tarabanovskaya L. A. Tashireva I. V. Deryusheva V. M. Perelmuter E. M. Slonimskaya N. V. Litviakov |
| author_facet | M. K. Ibragimova M. M. Tsyganov N. A. Tarabanovskaya L. A. Tashireva I. V. Deryusheva V. M. Perelmuter E. M. Slonimskaya N. V. Litviakov |
| author_sort | M. K. Ibragimova |
| collection | DOAJ |
| description | In this manuscript, a unique case of HPV16-positive breast cancer is examined. The presence of HPV infection in the tumor is confirmed by two independent methods (PCR and immunohistochemistry). It is shown that in the presence of adverse factors of prognosis (lymphogenous metastasis, high level of Ki67 expression, presence of chromotrypsis in the tumor, and high level of genetic instability), a patient with a HPV-positive breast tumor has more than 8-year disease-free survival. |
| format | Article |
| id | doaj-art-bd656d283f2840bc98f635b95269b1d3 |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2018-03-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-bd656d283f2840bc98f635b95269b1d32025-08-20T03:21:43ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842018-03-0117123223810.20538/1682-0363-2018-1-232-238780The clinical observation of human papillomavirus positive breast tumorM. K. Ibragimova0M. M. Tsyganov1N. A. Tarabanovskaya2L. A. Tashireva3I. V. Deryusheva4V. M. Perelmuter5E. M. Slonimskaya6N. V. Litviakov7Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) ; National Research Tomsk State University (NR TSU).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) .Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) .Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) .Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) .Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) .Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS); Siberian State Medical University (SSMU).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC) of Russian Academy of Sciences (RAS) ; National Research Tomsk State University (NR TSU).In this manuscript, a unique case of HPV16-positive breast cancer is examined. The presence of HPV infection in the tumor is confirmed by two independent methods (PCR and immunohistochemistry). It is shown that in the presence of adverse factors of prognosis (lymphogenous metastasis, high level of Ki67 expression, presence of chromotrypsis in the tumor, and high level of genetic instability), a patient with a HPV-positive breast tumor has more than 8-year disease-free survival.https://bulletin.ssmu.ru/jour/article/view/1133breast cancerhuman papillomavirusmicromatrix analysisprognosis |
| spellingShingle | M. K. Ibragimova M. M. Tsyganov N. A. Tarabanovskaya L. A. Tashireva I. V. Deryusheva V. M. Perelmuter E. M. Slonimskaya N. V. Litviakov The clinical observation of human papillomavirus positive breast tumor Бюллетень сибирской медицины breast cancer human papillomavirus micromatrix analysis prognosis |
| title | The clinical observation of human papillomavirus positive breast tumor |
| title_full | The clinical observation of human papillomavirus positive breast tumor |
| title_fullStr | The clinical observation of human papillomavirus positive breast tumor |
| title_full_unstemmed | The clinical observation of human papillomavirus positive breast tumor |
| title_short | The clinical observation of human papillomavirus positive breast tumor |
| title_sort | clinical observation of human papillomavirus positive breast tumor |
| topic | breast cancer human papillomavirus micromatrix analysis prognosis |
| url | https://bulletin.ssmu.ru/jour/article/view/1133 |
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