IGF-1 c.258 A > G synonymous mutation ameliorates senile osteoporosis

IGF-1 c.258 A > G synonymous mutation ameliorates senile osteoporosis

Abstract Senile osteoporosis (SOP) is a multifactorial, age-related progressive phenomenon with a considerable morbidity and mortality. IGF-1 is an important regulator of bone reconstruction and metabolism throughout life. Nevertheless, our previous study unexpectedly found there is no change in the...

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Main Authors: Zhaoguo Wang, Dayou Dai, Siyao Wang, Libo Zhang, Yi Li, Xunming Zhang, Yunyun Cheng, Linlin Hao
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07369-x
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