Negative interactions determine Clostridioides difficile growth in synthetic human gut communities

Abstract Understanding the principles of colonization resistance of the gut microbiome to the pathogen Clostridioides difficile will enable the design of defined bacterial therapeutics. We investigate the ecological principles of community resistance to C. difficile using a synthetic human gut micro...

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Bibliographic Details
Main Authors: Susan Hromada, Yili Qian, Tyler B Jacobson, Ryan L Clark, Lauren Watson, Nasia Safdar, Daniel Amador‐Noguez, Ophelia S Venturelli
Format: Article
Language:English
Published: Springer Nature 2021-10-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.202110355
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