A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room tempe...

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Main Authors: Hossein Anaraki-Ardakani, Maziar Noei, Mina Karbalaei-Harofteh, Shahab Zomorodbakhsh
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/915861
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author Hossein Anaraki-Ardakani
Maziar Noei
Mina Karbalaei-Harofteh
Shahab Zomorodbakhsh
author_facet Hossein Anaraki-Ardakani
Maziar Noei
Mina Karbalaei-Harofteh
Shahab Zomorodbakhsh
author_sort Hossein Anaraki-Ardakani
collection DOAJ
description A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.
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spelling doaj-art-bd5cd84463ba478593f2ff9b49f899f42025-08-20T03:23:31ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01942239224410.1155/2012/915861A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component ReactionHossein Anaraki-Ardakani0Maziar Noei1Mina Karbalaei-Harofteh2Shahab Zomorodbakhsh3Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, IranDepartment of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, IranDepartment of Chemistry, Islamic Azad University, Yazd Branch, P.O. Box 89195-155, Yazd, IranDepartment of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, IranA new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.http://dx.doi.org/10.1155/2012/915861
spellingShingle Hossein Anaraki-Ardakani
Maziar Noei
Mina Karbalaei-Harofteh
Shahab Zomorodbakhsh
A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
E-Journal of Chemistry
title A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
title_full A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
title_fullStr A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
title_full_unstemmed A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
title_short A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction
title_sort facile synthesis of polysubstituted pyrroles by one pot three component reaction
url http://dx.doi.org/10.1155/2012/915861
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