Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes
Objectives: The objective of this study was to evaluate if the diastolic reserve is different in prediabetes versus control during exercise. Materials and Methods: During the resting stage and graded supine bicycling exertion (25 W, 3 min increment), the mitral inflow and septal mitral annular veloc...
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Tzu Chi Medical Journal |
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| Online Access: | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=2;spage=188;epage=192;aulast=Jawad |
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| author | Abdulameer Jasim Jawad Al-Gburi |
| author_facet | Abdulameer Jasim Jawad Al-Gburi |
| author_sort | Abdulameer Jasim Jawad Al-Gburi |
| collection | DOAJ |
| description | Objectives: The objective of this study was to evaluate if the diastolic reserve is different in prediabetes versus control during exercise. Materials and Methods: During the resting stage and graded supine bicycling exertion (25 W, 3 min increment), the mitral inflow and septal mitral annular velocities were determined in 50 patients with prediabetes (21 females, mean age 48 ± 16 years) and 50 gender- and age-matched controls. None demonstrated rest or inducible cardiac ischemia on echocardiography. Results: Between the two study groups, the velocities of the mitral inflow (E) and septal mitral annulus (E′) at rest are not significantly different. E′ during exercise, on the other hand, was significantly lower in individuals with prediabetes than in controls (8.57 ± 2.46 vs. 9.82 ± 2.42 cm/s at 25 W, P = 0.012; 9.42 ± 1.93 vs. 11.15±2.97 cm/s at 50 W, P = 0.001). E/E′ behaves oppositely during exercise with a value that is significantly higher in patients with prediabetes. Conclusion: The diastolic reserve of the left ventricle, as determined by the change in E′ and E/E′ throughout exercise, is abnormal in individuals with prediabetes who do not have overt cardiac disease. Using exercise stress echocardiography may be helpful for the early recognition of subclinical diastolic dysfunction in prediabetics which may have clinical repercussions in the future. |
| format | Article |
| id | doaj-art-bd4e543e1f094ee9b3f19b7304b916a0 |
| institution | DOAJ |
| issn | 1016-3190 2223-8956 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Tzu Chi Medical Journal |
| spelling | doaj-art-bd4e543e1f094ee9b3f19b7304b916a02025-08-20T03:05:02ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562023-01-0135218819210.4103/tcmj.tcmj_151_22Left ventricular diastolic reserve by exercise stress echocardiography in prediabetesAbdulameer Jasim Jawad Al-GburiObjectives: The objective of this study was to evaluate if the diastolic reserve is different in prediabetes versus control during exercise. Materials and Methods: During the resting stage and graded supine bicycling exertion (25 W, 3 min increment), the mitral inflow and septal mitral annular velocities were determined in 50 patients with prediabetes (21 females, mean age 48 ± 16 years) and 50 gender- and age-matched controls. None demonstrated rest or inducible cardiac ischemia on echocardiography. Results: Between the two study groups, the velocities of the mitral inflow (E) and septal mitral annulus (E′) at rest are not significantly different. E′ during exercise, on the other hand, was significantly lower in individuals with prediabetes than in controls (8.57 ± 2.46 vs. 9.82 ± 2.42 cm/s at 25 W, P = 0.012; 9.42 ± 1.93 vs. 11.15±2.97 cm/s at 50 W, P = 0.001). E/E′ behaves oppositely during exercise with a value that is significantly higher in patients with prediabetes. Conclusion: The diastolic reserve of the left ventricle, as determined by the change in E′ and E/E′ throughout exercise, is abnormal in individuals with prediabetes who do not have overt cardiac disease. Using exercise stress echocardiography may be helpful for the early recognition of subclinical diastolic dysfunction in prediabetics which may have clinical repercussions in the future.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=2;spage=188;epage=192;aulast=Jawaddiastolic dysfunctionexercise stress echocardiographyimpaired fasting glucoseinsulin resistance |
| spellingShingle | Abdulameer Jasim Jawad Al-Gburi Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes Tzu Chi Medical Journal diastolic dysfunction exercise stress echocardiography impaired fasting glucose insulin resistance |
| title | Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes |
| title_full | Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes |
| title_fullStr | Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes |
| title_full_unstemmed | Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes |
| title_short | Left ventricular diastolic reserve by exercise stress echocardiography in prediabetes |
| title_sort | left ventricular diastolic reserve by exercise stress echocardiography in prediabetes |
| topic | diastolic dysfunction exercise stress echocardiography impaired fasting glucose insulin resistance |
| url | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=2;spage=188;epage=192;aulast=Jawad |
| work_keys_str_mv | AT abdulameerjasimjawadalgburi leftventriculardiastolicreservebyexercisestressechocardiographyinprediabetes |