A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY

While planning treatment and prevention in cardiovascular disorders (CVD) it is important to take into account the data on stability of clinical course of the main risk factors (RF). Until recently there is no such data on Russian population. Aim. To study the stability of arterial hypertension (AH)...

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Main Authors: I. V. Dolgalev, R. S. Karpov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2015-01-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/206
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author I. V. Dolgalev
R. S. Karpov
author_facet I. V. Dolgalev
R. S. Karpov
author_sort I. V. Dolgalev
collection DOAJ
description While planning treatment and prevention in cardiovascular disorders (CVD) it is important to take into account the data on stability of clinical course of the main risk factors (RF). Until recently there is no such data on Russian population. Aim. To study the stability of arterial hypertension (AH), overweight (OW), hypercholestrolemia (HCE), hypertriglyceridemia (HTE) among men and women in 17-year observation. Material and methods. Baseline testing on the base of randomly assigned selection from the city of Tomsk citizens was performed in 1988-1991 (1546 men and women 20-59 y.  o.). Second test was done in 2002-2005, and the data obtained on RF and endpoints in 81,2% persons from the first step. A stability factor (St) was defined as relation of repeated RF (RF2) to the general selection (RF1), in percent — St=RF2/RF1 x 100%. Also the regression of RF was calculated. As regression we defined the cases of nonfinding of RF in the second measurement while having this in the first, and calculated by 1000 person-years of observation (PEO). Results. Seventeen-years lasting prospective study, performed on the cohort of men and women 20-59 y.  o. showed a high stability of AH, OW, HCE. The St values for AH was 96,6% (regressed 2,31 cases by 1000 PEO), for HCE; St for OW — 92,7% (regressed 4,70 by 1000 PEO); St for HCE — 92,9% (regressed 4,53 by 1000 PEO). HTE was not so stable RF: St = 75,0%. In age subgroup of 20-29 y. the interrelation of lower stability for HCE and HTE was found — St for HCE was 85,0% (regression 9,37 cases by 1000 PEO); St for HTE — 50,0% (regression 30,38 per 1000 PEO). It suggests that the nonmedication methods for dyslipoproteidemia correction, as diet, physical exertion increase, smoking cessation, body mass decrease can be highly effective in young people.
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spelling doaj-art-bd403e695d6048f6b1d7a909323bdecb2025-08-20T03:35:11Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202015-01-0101677110.15829/1560-4071-2015-1-67-71206A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDYI. V. Dolgalev0R. S. Karpov1Siberian State Medical University, Tomsk, RussiaSiberian State Medical University, Tomsk, RussiaWhile planning treatment and prevention in cardiovascular disorders (CVD) it is important to take into account the data on stability of clinical course of the main risk factors (RF). Until recently there is no such data on Russian population. Aim. To study the stability of arterial hypertension (AH), overweight (OW), hypercholestrolemia (HCE), hypertriglyceridemia (HTE) among men and women in 17-year observation. Material and methods. Baseline testing on the base of randomly assigned selection from the city of Tomsk citizens was performed in 1988-1991 (1546 men and women 20-59 y.  o.). Second test was done in 2002-2005, and the data obtained on RF and endpoints in 81,2% persons from the first step. A stability factor (St) was defined as relation of repeated RF (RF2) to the general selection (RF1), in percent — St=RF2/RF1 x 100%. Also the regression of RF was calculated. As regression we defined the cases of nonfinding of RF in the second measurement while having this in the first, and calculated by 1000 person-years of observation (PEO). Results. Seventeen-years lasting prospective study, performed on the cohort of men and women 20-59 y.  o. showed a high stability of AH, OW, HCE. The St values for AH was 96,6% (regressed 2,31 cases by 1000 PEO), for HCE; St for OW — 92,7% (regressed 4,70 by 1000 PEO); St for HCE — 92,9% (regressed 4,53 by 1000 PEO). HTE was not so stable RF: St = 75,0%. In age subgroup of 20-29 y. the interrelation of lower stability for HCE and HTE was found — St for HCE was 85,0% (regression 9,37 cases by 1000 PEO); St for HTE — 50,0% (regression 30,38 per 1000 PEO). It suggests that the nonmedication methods for dyslipoproteidemia correction, as diet, physical exertion increase, smoking cessation, body mass decrease can be highly effective in young people.https://russjcardiol.elpub.ru/jour/article/view/206descriptive epidemiologyprospective studyrisk factorsarterial hypertensionoverweightdyslipoproteidemia
spellingShingle I. V. Dolgalev
R. S. Karpov
A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY
Российский кардиологический журнал
descriptive epidemiology
prospective study
risk factors
arterial hypertension
overweight
dyslipoproteidemia
title A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY
title_full A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY
title_fullStr A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY
title_full_unstemmed A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY
title_short A STABILITY OF CARDIOVASCULAR RISK FACTORS BY THE 17-YEAR OBSERVATIONAL STUDY
title_sort stability of cardiovascular risk factors by the 17 year observational study
topic descriptive epidemiology
prospective study
risk factors
arterial hypertension
overweight
dyslipoproteidemia
url https://russjcardiol.elpub.ru/jour/article/view/206
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