Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man
Insulin autoimmune syndrome (IAS) is a disease characterized by hyperinsulinaemic hypoglycaemia associated with autoantibodies against endogenous insulin. We have described a case of a 25-year-old, previously healthy Kuwaiti man who was admitted to the Mubarak Al-Kabeer hospital with a history of re...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2019/8919457 |
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| author | Einas Alrashidi Thamer Alessa |
| author_facet | Einas Alrashidi Thamer Alessa |
| author_sort | Einas Alrashidi |
| collection | DOAJ |
| description | Insulin autoimmune syndrome (IAS) is a disease characterized by hyperinsulinaemic hypoglycaemia associated with autoantibodies against endogenous insulin. We have described a case of a 25-year-old, previously healthy Kuwaiti man who was admitted to the Mubarak Al-Kabeer hospital with a history of recurrent hypoglycaemia. The patient revealed that he had taken several different injectable anabolic steroids and growth hormone with oral amino acids and other tablets (fat burners) for bodybuilding in the last two months. He denied knowingly using insulin or insulin analogues. The patient had elevated fasting insulin level (>301 uIU/mL) and elevated insulin autoantibodies (>100.0 IU/mL). After appropriate work-up, he was diagnosed with IAS. After treatment with prednisolone (1 mg/kg/day), the patient had complete recovery. In patients with repeated hypoglycaemia, IAS should be considered in the differential diagnosis. Glucocorticoid therapy can be effective for the treatment of hypoglycaemia in patients with IAS. |
| format | Article |
| id | doaj-art-bd3f65a81b5f4a96995b88822c86c38a |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-bd3f65a81b5f4a96995b88822c86c38a2025-02-03T01:30:18ZengWileyCase Reports in Endocrinology2090-65012090-651X2019-01-01201910.1155/2019/89194578919457Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti ManEinas Alrashidi0Thamer Alessa1Department of Internal Medicine, Al-Farwaniya Hospital, KuwaitDivision of Endocrinology, Diabetes and Metabolism, Jaber Al-Ahmad Hospital, KuwaitInsulin autoimmune syndrome (IAS) is a disease characterized by hyperinsulinaemic hypoglycaemia associated with autoantibodies against endogenous insulin. We have described a case of a 25-year-old, previously healthy Kuwaiti man who was admitted to the Mubarak Al-Kabeer hospital with a history of recurrent hypoglycaemia. The patient revealed that he had taken several different injectable anabolic steroids and growth hormone with oral amino acids and other tablets (fat burners) for bodybuilding in the last two months. He denied knowingly using insulin or insulin analogues. The patient had elevated fasting insulin level (>301 uIU/mL) and elevated insulin autoantibodies (>100.0 IU/mL). After appropriate work-up, he was diagnosed with IAS. After treatment with prednisolone (1 mg/kg/day), the patient had complete recovery. In patients with repeated hypoglycaemia, IAS should be considered in the differential diagnosis. Glucocorticoid therapy can be effective for the treatment of hypoglycaemia in patients with IAS.http://dx.doi.org/10.1155/2019/8919457 |
| spellingShingle | Einas Alrashidi Thamer Alessa Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man Case Reports in Endocrinology |
| title | Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man |
| title_full | Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man |
| title_fullStr | Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man |
| title_full_unstemmed | Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man |
| title_short | Insulin Autoimmune Syndrome in a 25-Year-Old, Previously Healthy Kuwaiti Man |
| title_sort | insulin autoimmune syndrome in a 25 year old previously healthy kuwaiti man |
| url | http://dx.doi.org/10.1155/2019/8919457 |
| work_keys_str_mv | AT einasalrashidi insulinautoimmunesyndromeina25yearoldpreviouslyhealthykuwaitiman AT thameralessa insulinautoimmunesyndromeina25yearoldpreviouslyhealthykuwaitiman |