Dental Resin Composites Modified with Chitosan: A Systematic Review
Objective: This systematic review aims to evaluate the impact of incorporating chitosan into dental resin composites on their mechanical, antibacterial, and physicochemical properties. Methods: A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted in March 2025 using t...
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MDPI AG
2025-05-01
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| Online Access: | https://www.mdpi.com/1660-3397/23/5/199 |
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| author | Wojciech Dobrzyński Paweł J. Piszko Jan Kiryk Sylwia Kiryk Mateusz Michalak Agnieszka Kotela Julia Kensy Witold Świenc Natalia Grychowska Jacek Matys Maciej Dobrzyński |
| author_facet | Wojciech Dobrzyński Paweł J. Piszko Jan Kiryk Sylwia Kiryk Mateusz Michalak Agnieszka Kotela Julia Kensy Witold Świenc Natalia Grychowska Jacek Matys Maciej Dobrzyński |
| author_sort | Wojciech Dobrzyński |
| collection | DOAJ |
| description | Objective: This systematic review aims to evaluate the impact of incorporating chitosan into dental resin composites on their mechanical, antibacterial, and physicochemical properties. Methods: A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted in March 2025 using the following keywords: resin, composite, and chitosan. The inclusion criteria comprised in vitro studies in dentistry evaluating chitosan as a composite additive with full-text availability in English. Data extraction and quality assessment were performed independently by multiple reviewers using standardized tools, and study quality was assessed based on predefined criteria. Results: Seventeen studies met the inclusion criteria. Chitosan concentrations in the composites ranged from 0.25 wt% to 20 wt%. Antibacterial activity was confirmed in six studies, especially against <i>S. mutans</i>, <i>S. sanguinis</i>, and <i>L. acidophilus</i>. Mechanical properties such as fracture toughness, hardness, and compressive strength were generally improved at lower concentrations of chitosan. However, increased chitosan levels were associated with decreased flexural strength and increased microleakage. Shear bond strength (SBS) was unaffected by chitosan in low concentrations (up to 0.25%), while higher concentrations reduced SBS. Fluoride release capacity was assessed in one study, with no significant differences observed. Conclusion: Chitosan-modified dental resin composites exhibit promising antibacterial and mechanical enhancements at low concentrations. However, higher chitosan levels may compromise certain mechanical and adhesive properties. These findings suggest a need for standardized methodologies and further research on long-term clinical implications and fluoride release. |
| format | Article |
| id | doaj-art-bd3e1648d494475b9121420e5578829f |
| institution | OA Journals |
| issn | 1660-3397 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj-art-bd3e1648d494475b9121420e5578829f2025-08-20T02:34:01ZengMDPI AGMarine Drugs1660-33972025-05-0123519910.3390/md23050199Dental Resin Composites Modified with Chitosan: A Systematic ReviewWojciech Dobrzyński0Paweł J. Piszko1Jan Kiryk2Sylwia Kiryk3Mateusz Michalak4Agnieszka Kotela5Julia Kensy6Witold Świenc7Natalia Grychowska8Jacek Matys9Maciej Dobrzyński10Department of Dentofacial Orthopedics and Orthodontics, Division of Facial Abnormalities, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, PolandDental Surgery Department, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandDepartment of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandMedical Center of Innovation, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandMedical Center of Innovation, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandFaculty of Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandMedical Center of Innovation, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandDepartment of Dental Prosthetics, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandDental Surgery Department, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandDepartment of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandObjective: This systematic review aims to evaluate the impact of incorporating chitosan into dental resin composites on their mechanical, antibacterial, and physicochemical properties. Methods: A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted in March 2025 using the following keywords: resin, composite, and chitosan. The inclusion criteria comprised in vitro studies in dentistry evaluating chitosan as a composite additive with full-text availability in English. Data extraction and quality assessment were performed independently by multiple reviewers using standardized tools, and study quality was assessed based on predefined criteria. Results: Seventeen studies met the inclusion criteria. Chitosan concentrations in the composites ranged from 0.25 wt% to 20 wt%. Antibacterial activity was confirmed in six studies, especially against <i>S. mutans</i>, <i>S. sanguinis</i>, and <i>L. acidophilus</i>. Mechanical properties such as fracture toughness, hardness, and compressive strength were generally improved at lower concentrations of chitosan. However, increased chitosan levels were associated with decreased flexural strength and increased microleakage. Shear bond strength (SBS) was unaffected by chitosan in low concentrations (up to 0.25%), while higher concentrations reduced SBS. Fluoride release capacity was assessed in one study, with no significant differences observed. Conclusion: Chitosan-modified dental resin composites exhibit promising antibacterial and mechanical enhancements at low concentrations. However, higher chitosan levels may compromise certain mechanical and adhesive properties. These findings suggest a need for standardized methodologies and further research on long-term clinical implications and fluoride release.https://www.mdpi.com/1660-3397/23/5/199antibacterialchitosanmechanical propertiesresin composite |
| spellingShingle | Wojciech Dobrzyński Paweł J. Piszko Jan Kiryk Sylwia Kiryk Mateusz Michalak Agnieszka Kotela Julia Kensy Witold Świenc Natalia Grychowska Jacek Matys Maciej Dobrzyński Dental Resin Composites Modified with Chitosan: A Systematic Review Marine Drugs antibacterial chitosan mechanical properties resin composite |
| title | Dental Resin Composites Modified with Chitosan: A Systematic Review |
| title_full | Dental Resin Composites Modified with Chitosan: A Systematic Review |
| title_fullStr | Dental Resin Composites Modified with Chitosan: A Systematic Review |
| title_full_unstemmed | Dental Resin Composites Modified with Chitosan: A Systematic Review |
| title_short | Dental Resin Composites Modified with Chitosan: A Systematic Review |
| title_sort | dental resin composites modified with chitosan a systematic review |
| topic | antibacterial chitosan mechanical properties resin composite |
| url | https://www.mdpi.com/1660-3397/23/5/199 |
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