Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection
Sickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregna...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Asian Journal of Transfusion Science |
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| Online Access: | https://journals.lww.com/10.4103/ajts.ajts_164_21 |
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| author | Vaidyanathan Gowri Tamima Al Dughaishi Deepti Geetha Marwa Al Riyami Radhiya Alburaidi Salam Al Kindi |
| author_facet | Vaidyanathan Gowri Tamima Al Dughaishi Deepti Geetha Marwa Al Riyami Radhiya Alburaidi Salam Al Kindi |
| author_sort | Vaidyanathan Gowri |
| collection | DOAJ |
| description | Sickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregnancy in SCA with COVID is scarce. We report a case series study of pregnant women with SCA, who are confirmed positive for COVID-19 from May 2020 to March 2021. These patients showed generally mild-to-moderate disease and presented predominantly with fever and painful crisis. They showed a significant drop in Hb from baseline, and they received low-molecular-weight heparin prophylaxis (LMWH) and blood transfusion. The outcome of pregnancy is satisfactory, although the mean birth weight was significantly lower than that reported from the same SCA population. |
| format | Article |
| id | doaj-art-bd3bb4148bea4474ae28310c3b790e32 |
| institution | Kabale University |
| issn | 0973-6247 1998-3565 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Transfusion Science |
| spelling | doaj-art-bd3bb4148bea4474ae28310c3b790e322025-01-20T09:40:55ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-01-0118114414710.4103/ajts.ajts_164_21Outcome of pregnancy in sickle cell anemia patients with COVID-19 infectionVaidyanathan GowriTamima Al DughaishiDeepti GeethaMarwa Al RiyamiRadhiya AlburaidiSalam Al KindiSickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregnancy in SCA with COVID is scarce. We report a case series study of pregnant women with SCA, who are confirmed positive for COVID-19 from May 2020 to March 2021. These patients showed generally mild-to-moderate disease and presented predominantly with fever and painful crisis. They showed a significant drop in Hb from baseline, and they received low-molecular-weight heparin prophylaxis (LMWH) and blood transfusion. The outcome of pregnancy is satisfactory, although the mean birth weight was significantly lower than that reported from the same SCA population.https://journals.lww.com/10.4103/ajts.ajts_164_21coronavirus disease 2019pregnancysevere acute respiratory syndrome coronavirus 2sickle cell anemia |
| spellingShingle | Vaidyanathan Gowri Tamima Al Dughaishi Deepti Geetha Marwa Al Riyami Radhiya Alburaidi Salam Al Kindi Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection Asian Journal of Transfusion Science coronavirus disease 2019 pregnancy severe acute respiratory syndrome coronavirus 2 sickle cell anemia |
| title | Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection |
| title_full | Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection |
| title_fullStr | Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection |
| title_full_unstemmed | Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection |
| title_short | Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection |
| title_sort | outcome of pregnancy in sickle cell anemia patients with covid 19 infection |
| topic | coronavirus disease 2019 pregnancy severe acute respiratory syndrome coronavirus 2 sickle cell anemia |
| url | https://journals.lww.com/10.4103/ajts.ajts_164_21 |
| work_keys_str_mv | AT vaidyanathangowri outcomeofpregnancyinsicklecellanemiapatientswithcovid19infection AT tamimaaldughaishi outcomeofpregnancyinsicklecellanemiapatientswithcovid19infection AT deeptigeetha outcomeofpregnancyinsicklecellanemiapatientswithcovid19infection AT marwaalriyami outcomeofpregnancyinsicklecellanemiapatientswithcovid19infection AT radhiyaalburaidi outcomeofpregnancyinsicklecellanemiapatientswithcovid19infection AT salamalkindi outcomeofpregnancyinsicklecellanemiapatientswithcovid19infection |