Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection

Sickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregna...

Full description

Saved in:
Bibliographic Details
Main Authors: Vaidyanathan Gowri, Tamima Al Dughaishi, Deepti Geetha, Marwa Al Riyami, Radhiya Alburaidi, Salam Al Kindi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:https://journals.lww.com/10.4103/ajts.ajts_164_21
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregnancy in SCA with COVID is scarce. We report a case series study of pregnant women with SCA, who are confirmed positive for COVID-19 from May 2020 to March 2021. These patients showed generally mild-to-moderate disease and presented predominantly with fever and painful crisis. They showed a significant drop in Hb from baseline, and they received low-molecular-weight heparin prophylaxis (LMWH) and blood transfusion. The outcome of pregnancy is satisfactory, although the mean birth weight was significantly lower than that reported from the same SCA population.
ISSN:0973-6247
1998-3565