Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)

In the tenth year since the first edition of MISEV was released in 2014, MISEV2023 has been reported in 2024 with the aim of refining the standard and improving the rigor, reproducibility, and transparency of extracellular vesicle (EV) research to clarify the requirements for experimental design of...

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Main Authors: Yuan Zhang, Mengyi Lan, Yong Chen
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/16/11/1394
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author Yuan Zhang
Mengyi Lan
Yong Chen
author_facet Yuan Zhang
Mengyi Lan
Yong Chen
author_sort Yuan Zhang
collection DOAJ
description In the tenth year since the first edition of MISEV was released in 2014, MISEV2023 has been reported in 2024 with the aim of refining the standard and improving the rigor, reproducibility, and transparency of extracellular vesicle (EV) research to clarify the requirements for experimental design of EVs, emphasize the importance of reproducible experimental results as well as encouraging openness of experimental information. The release of MISEV has significantly contributed to the quality of research in the field of EVs, which creates a more reliable research environment. However, despite the important role of MISEV, there is still a need for the EV researchers to continue to push for the widespread implementation of the guidelines to meet the evolving nature and challenges of EV research. The evolution of EV research and the attention it receives have grown exponentially over time, as has the number of people involved in the writing of MISEV. Here, this review briefly summarizes the evolution of the three editions of MISEV, aiming to recall MISEV2014 and MISEV2018 while learning about the latest release, MISEV2023, to gain a deeper understanding of the content, and to provide a quick note for beginners who want to learn about MISEV and explore the EV world.
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spelling doaj-art-bd3360b21dc64172a3ca5c4747cdcd302025-08-20T02:48:02ZengMDPI AGPharmaceutics1999-49232024-10-011611139410.3390/pharmaceutics16111394Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)Yuan Zhang0Mengyi Lan1Yong Chen2School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang 330006, ChinaIn the tenth year since the first edition of MISEV was released in 2014, MISEV2023 has been reported in 2024 with the aim of refining the standard and improving the rigor, reproducibility, and transparency of extracellular vesicle (EV) research to clarify the requirements for experimental design of EVs, emphasize the importance of reproducible experimental results as well as encouraging openness of experimental information. The release of MISEV has significantly contributed to the quality of research in the field of EVs, which creates a more reliable research environment. However, despite the important role of MISEV, there is still a need for the EV researchers to continue to push for the widespread implementation of the guidelines to meet the evolving nature and challenges of EV research. The evolution of EV research and the attention it receives have grown exponentially over time, as has the number of people involved in the writing of MISEV. Here, this review briefly summarizes the evolution of the three editions of MISEV, aiming to recall MISEV2014 and MISEV2018 while learning about the latest release, MISEV2023, to gain a deeper understanding of the content, and to provide a quick note for beginners who want to learn about MISEV and explore the EV world.https://www.mdpi.com/1999-4923/16/11/1394extracellular vesicles (EVs)international society for extracellular vesicles (ISEV)minimal information for studies of extracellular vesicles (MISEV)exosomesectosomesmicrovesicles
spellingShingle Yuan Zhang
Mengyi Lan
Yong Chen
Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)
Pharmaceutics
extracellular vesicles (EVs)
international society for extracellular vesicles (ISEV)
minimal information for studies of extracellular vesicles (MISEV)
exosomes
ectosomes
microvesicles
title Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)
title_full Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)
title_fullStr Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)
title_full_unstemmed Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)
title_short Minimal Information for Studies of Extracellular Vesicles (MISEV): Ten-Year Evolution (2014–2023)
title_sort minimal information for studies of extracellular vesicles misev ten year evolution 2014 2023
topic extracellular vesicles (EVs)
international society for extracellular vesicles (ISEV)
minimal information for studies of extracellular vesicles (MISEV)
exosomes
ectosomes
microvesicles
url https://www.mdpi.com/1999-4923/16/11/1394
work_keys_str_mv AT yuanzhang minimalinformationforstudiesofextracellularvesiclesmisevtenyearevolution20142023
AT mengyilan minimalinformationforstudiesofextracellularvesiclesmisevtenyearevolution20142023
AT yongchen minimalinformationforstudiesofextracellularvesiclesmisevtenyearevolution20142023