Role of adjuvant therapy in the treatment of helicobacter pylori infection in children
The aim was to study the effect of combined probiotic containing Lactobacillus acidophilus, Bifidobacterium infantis, Enterococcus faecium, on H.pylori eradication efficacy in the treatment of children with chronic H.pylori- associated gastroduodenitis in the scheme of "triple" therapy of...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2014-06-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://medpers.dsma.dp.ua/issues/2014/N2/97-102.pdf |
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| author | Gerasymenko O.N. |
| author_facet | Gerasymenko O.N. |
| author_sort | Gerasymenko O.N. |
| collection | DOAJ |
| description | The aim was to study the effect of combined probiotic containing Lactobacillus acidophilus, Bifidobacterium infantis, Enterococcus faecium, on H.pylori eradication efficacy in the treatment of children with chronic H.pylori- associated gastroduodenitis in the scheme of "triple" therapy of H.pylori eradication. Determination of total serum Ig M , A, G protein to Ag SagA H. pylori, breathing "Helik" test, rapid urease "Helpil" test ; that of concentration of serum sCD14 was conducted. The study group included 20 children who received standard "triple" eradication therapy for 7 days and 1 caps. of probiotic 3 times a day for 4 weeks, control group (20 children) – who received only standard eradication therapy. It is shown that combined use of probiotics in the treatment of Helicobacter pylori infection enhances effectiveness of eradication of H.pylori. In the basis of action of probiotic strains of the drug is an anti-inflammatory effect mediated by the impact on non-specific mechanisms of innate immunity, provided by molecular mechanism responsible for induction of sCD14 synthesis. |
| format | Article |
| id | doaj-art-bd2fc863ff064a25a472c62ff07ca355 |
| institution | DOAJ |
| issn | 2307-0404 2307-0404 |
| language | English |
| publishDate | 2014-06-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-bd2fc863ff064a25a472c62ff07ca3552025-08-20T02:50:48ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042307-04042014-06-0119297102Role of adjuvant therapy in the treatment of helicobacter pylori infection in childrenGerasymenko O.N. 0SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»The aim was to study the effect of combined probiotic containing Lactobacillus acidophilus, Bifidobacterium infantis, Enterococcus faecium, on H.pylori eradication efficacy in the treatment of children with chronic H.pylori- associated gastroduodenitis in the scheme of "triple" therapy of H.pylori eradication. Determination of total serum Ig M , A, G protein to Ag SagA H. pylori, breathing "Helik" test, rapid urease "Helpil" test ; that of concentration of serum sCD14 was conducted. The study group included 20 children who received standard "triple" eradication therapy for 7 days and 1 caps. of probiotic 3 times a day for 4 weeks, control group (20 children) – who received only standard eradication therapy. It is shown that combined use of probiotics in the treatment of Helicobacter pylori infection enhances effectiveness of eradication of H.pylori. In the basis of action of probiotic strains of the drug is an anti-inflammatory effect mediated by the impact on non-specific mechanisms of innate immunity, provided by molecular mechanism responsible for induction of sCD14 synthesis.http://medpers.dsma.dp.ua/issues/2014/N2/97-102.pdfchildrenchronic gastroduodenitisHelicobacter pylorieradicationprobioticsCD14 |
| spellingShingle | Gerasymenko O.N. Role of adjuvant therapy in the treatment of helicobacter pylori infection in children Medičnì Perspektivi children chronic gastroduodenitis Helicobacter pylori eradication probiotic sCD14 |
| title | Role of adjuvant therapy in the treatment of helicobacter pylori infection in children |
| title_full | Role of adjuvant therapy in the treatment of helicobacter pylori infection in children |
| title_fullStr | Role of adjuvant therapy in the treatment of helicobacter pylori infection in children |
| title_full_unstemmed | Role of adjuvant therapy in the treatment of helicobacter pylori infection in children |
| title_short | Role of adjuvant therapy in the treatment of helicobacter pylori infection in children |
| title_sort | role of adjuvant therapy in the treatment of helicobacter pylori infection in children |
| topic | children chronic gastroduodenitis Helicobacter pylori eradication probiotic sCD14 |
| url | http://medpers.dsma.dp.ua/issues/2014/N2/97-102.pdf |
| work_keys_str_mv | AT gerasymenkoon roleofadjuvanttherapyinthetreatmentofhelicobacterpyloriinfectioninchildren |