Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements

Intermediate- and advanced-stage hepatocellular carcinoma (HCC) continues to present significant therapeutic challenges. Hepatic artery infusion chemotherapy (HAIC), a well-established locoregional treatment for unresectable HCC, has recently demonstrated promising clinical outcomes both as monother...

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Main Authors: Wei Xu, Qing Li, Bin Liang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/32/6/313
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author Wei Xu
Qing Li
Bin Liang
author_facet Wei Xu
Qing Li
Bin Liang
author_sort Wei Xu
collection DOAJ
description Intermediate- and advanced-stage hepatocellular carcinoma (HCC) continues to present significant therapeutic challenges. Hepatic artery infusion chemotherapy (HAIC), a well-established locoregional treatment for unresectable HCC, has recently demonstrated promising clinical outcomes both as monotherapy and in combination with systemic therapies. This comprehensive review examines recent clinical advances in HAIC for HCC, with particular emphasis on evolving treatment regimens and their therapeutic efficacy.
format Article
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institution Kabale University
issn 1198-0052
1718-7729
language English
publishDate 2025-05-01
publisher MDPI AG
record_format Article
series Current Oncology
spelling doaj-art-bd2ef24d06044ab18577414104ce60fa2025-08-20T03:24:32ZengMDPI AGCurrent Oncology1198-00521718-77292025-05-0132631310.3390/curroncol32060313Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical AdvancementsWei Xu0Qing Li1Bin Liang2Hubei Provincial Clinical Research Center for Precision Radiology & Interventional Medicine, Hubei Key Laboratory of Molecular Imaging, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, ChinaDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou 215006, ChinaHubei Provincial Clinical Research Center for Precision Radiology & Interventional Medicine, Hubei Key Laboratory of Molecular Imaging, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan 430022, ChinaIntermediate- and advanced-stage hepatocellular carcinoma (HCC) continues to present significant therapeutic challenges. Hepatic artery infusion chemotherapy (HAIC), a well-established locoregional treatment for unresectable HCC, has recently demonstrated promising clinical outcomes both as monotherapy and in combination with systemic therapies. This comprehensive review examines recent clinical advances in HAIC for HCC, with particular emphasis on evolving treatment regimens and their therapeutic efficacy.https://www.mdpi.com/1718-7729/32/6/313hepatocellular carcinomahepatic artery infusion chemotherapylocoregional therapycombination therapy
spellingShingle Wei Xu
Qing Li
Bin Liang
Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements
Current Oncology
hepatocellular carcinoma
hepatic artery infusion chemotherapy
locoregional therapy
combination therapy
title Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements
title_full Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements
title_fullStr Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements
title_full_unstemmed Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements
title_short Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements
title_sort hepatic artery infusion chemotherapy for hepatocellular carcinoma clinical advancements
topic hepatocellular carcinoma
hepatic artery infusion chemotherapy
locoregional therapy
combination therapy
url https://www.mdpi.com/1718-7729/32/6/313
work_keys_str_mv AT weixu hepaticarteryinfusionchemotherapyforhepatocellularcarcinomaclinicaladvancements
AT qingli hepaticarteryinfusionchemotherapyforhepatocellularcarcinomaclinicaladvancements
AT binliang hepaticarteryinfusionchemotherapyforhepatocellularcarcinomaclinicaladvancements