Survival motor neuron protein regulates stem cell division, proliferation, and differentiation in Drosophila.

Spinal muscular atrophy is a severe neurogenic disease that is caused by mutations in the human survival motor neuron 1 (SMN1) gene. SMN protein is required for the assembly of small nuclear ribonucleoproteins and a dramatic reduction of the protein leads to cell death. It is currently unknown how t...

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Bibliographic Details
Main Authors: Stuart J Grice, Ji-Long Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002030&type=printable
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