Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery
Background: To systematically evaluate risk factors for stress-induced hyperglycemia in patients without diabetes after cardiac surgery. Methods: Databases including CNKI, WanFang data, VIP, SinoMed, PubMed, Web...
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| Format: | Article |
| Language: | English |
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IMR Press
2025-01-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25485 |
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| _version_ | 1832586532134846464 |
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| author | Mengli Zhang Ziyi Zhang Ningning Zhu Lulu Wang Hui Huang Yike Wang Fang Xue |
| author_facet | Mengli Zhang Ziyi Zhang Ningning Zhu Lulu Wang Hui Huang Yike Wang Fang Xue |
| author_sort | Mengli Zhang |
| collection | DOAJ |
| description | Background: To systematically evaluate risk factors for stress-induced hyperglycemia in patients without diabetes after cardiac surgery. Methods: Databases including CNKI, WanFang data, VIP, SinoMed, PubMed, Web of Science, Embase, and the Cochrane Library were searched using computer retrieval. The data were subjected to an in-depth meta-analysis using RevMan 5.4 and Stata 15.0 software. Results: This study involved 11,645 postoperative cardiac surgery patients, including 8 case-control studies and 3 cohort studies, over which 18 risk factors were identified. The results of the meta-analysis indicated that statistically significant risk factors included age >65 years [odds ratios (OR) (95% CI ) = 3.47 (2.61–4.32)], female gender [OR (95%) = 1.54 (1.34–1.76)], combined heart valve and coronary artery bypass surgery [OR (95%) = 1.82 (1.23–2.70)], ejection fraction <40% [OR (95%) = 1.38 (1.17–1.63)], history of heart surgery [OR (95%) = 1.30 (1.06–1.59)], myocardial infarction [OR (95%) = 1.17 (1.05–1.31)], hyperlipidemia [OR (95%) = 0.76 (0.67–0.86)], hypertension [OR (95%) = 1.12 (1.03–1.22)], anticoagulant medication [OR (95%) = 0.77 (0.65–0.90)], cardiopulmonary bypass time >2 hours [OR (95%) = 20.26 (17.03–23.48)] and history of cardiopulmonary bypass [OR (95%) = 1.24 (1.09–1.41)]. Conclusions: Current evidence suggests that there are key risk factors for postoperative stress hyperglycemia in patients without diabetes who have undergone cardiac surgery. These factors can help identify patients at a high risk of perioperative stress hyperglycemia during cardiac surgery. This evidence provides a basis for healthcare professionals to develop predictive management strategies for perioperative stress hyperglycemia in patients without diabetes. However, more high-quality studies are required to address the limitations of the current research. The PROSPERO registration: CRD42024479215, https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=479215. |
| format | Article |
| id | doaj-art-bd1fbf0e8c0d41d8b5ddbfb217bcb4e7 |
| institution | Kabale University |
| issn | 1530-6550 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj-art-bd1fbf0e8c0d41d8b5ddbfb217bcb4e72025-01-25T10:41:20ZengIMR PressReviews in Cardiovascular Medicine1530-65502025-01-012612548510.31083/RCM25485S1530-6550(24)01614-4Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac SurgeryMengli Zhang0Ziyi Zhang1Ningning Zhu2Lulu Wang3Hui Huang4Yike Wang5Fang Xue6School of Nursing, Bengbu Medical University, 233030 Bengbu, Anhui, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Bengbu Medical University, 233000 Bengbu, Anhui, ChinaSchool of Nursing, Bengbu Medical University, 233030 Bengbu, Anhui, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Bengbu Medical University, 233000 Bengbu, Anhui, ChinaDepartment of Cardiac Surgery, The First Affiliated Hospital of Bengbu Medical University, 233000 Bengbu, Anhui, ChinaClinical Medical School, Zhengzhou University, 450001 Zhengzhou, Henan, ChinaSchool of Nursing, Bengbu Medical University, 233030 Bengbu, Anhui, ChinaBackground: To systematically evaluate risk factors for stress-induced hyperglycemia in patients without diabetes after cardiac surgery. Methods: Databases including CNKI, WanFang data, VIP, SinoMed, PubMed, Web of Science, Embase, and the Cochrane Library were searched using computer retrieval. The data were subjected to an in-depth meta-analysis using RevMan 5.4 and Stata 15.0 software. Results: This study involved 11,645 postoperative cardiac surgery patients, including 8 case-control studies and 3 cohort studies, over which 18 risk factors were identified. The results of the meta-analysis indicated that statistically significant risk factors included age >65 years [odds ratios (OR) (95% CI ) = 3.47 (2.61–4.32)], female gender [OR (95%) = 1.54 (1.34–1.76)], combined heart valve and coronary artery bypass surgery [OR (95%) = 1.82 (1.23–2.70)], ejection fraction <40% [OR (95%) = 1.38 (1.17–1.63)], history of heart surgery [OR (95%) = 1.30 (1.06–1.59)], myocardial infarction [OR (95%) = 1.17 (1.05–1.31)], hyperlipidemia [OR (95%) = 0.76 (0.67–0.86)], hypertension [OR (95%) = 1.12 (1.03–1.22)], anticoagulant medication [OR (95%) = 0.77 (0.65–0.90)], cardiopulmonary bypass time >2 hours [OR (95%) = 20.26 (17.03–23.48)] and history of cardiopulmonary bypass [OR (95%) = 1.24 (1.09–1.41)]. Conclusions: Current evidence suggests that there are key risk factors for postoperative stress hyperglycemia in patients without diabetes who have undergone cardiac surgery. These factors can help identify patients at a high risk of perioperative stress hyperglycemia during cardiac surgery. This evidence provides a basis for healthcare professionals to develop predictive management strategies for perioperative stress hyperglycemia in patients without diabetes. However, more high-quality studies are required to address the limitations of the current research. The PROSPERO registration: CRD42024479215, https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=479215.https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25485cardiac surgerystress-induced hyperglycemiarisk factorssystematic review and meta-analysis |
| spellingShingle | Mengli Zhang Ziyi Zhang Ningning Zhu Lulu Wang Hui Huang Yike Wang Fang Xue Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery Reviews in Cardiovascular Medicine cardiac surgery stress-induced hyperglycemia risk factors systematic review and meta-analysis |
| title | Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery |
| title_full | Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery |
| title_fullStr | Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery |
| title_full_unstemmed | Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery |
| title_short | Systematic Review and Meta-Analysis of Risk Factors Associated with Postoperative Stress Hyperglycemia in Patients without Diabetes Following Cardiac Surgery |
| title_sort | systematic review and meta analysis of risk factors associated with postoperative stress hyperglycemia in patients without diabetes following cardiac surgery |
| topic | cardiac surgery stress-induced hyperglycemia risk factors systematic review and meta-analysis |
| url | https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25485 |
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