Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters

This research aimed to investigate the optimization of lipid-based nanoparticles to improve the utilization of n-3 PUFA source in chicken diets. Three groups of slow-growing Korat chickens were reared under the same conditions and fed a diet containing 6 % rice bran oil (RBO, control group), 3 % tun...

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Main Authors: Piyaradtana Homyok, Wunpen Sonsamrong, Nitipol Chainet, Wichuta Khosinklang, Anyanee Kamkaew, Teerapong Yata, Elisabeth Baéza, Cécile Berri, Amonrat Molee, Wittawat Molee
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Poultry Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125002214
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author Piyaradtana Homyok
Wunpen Sonsamrong
Nitipol Chainet
Wichuta Khosinklang
Anyanee Kamkaew
Teerapong Yata
Elisabeth Baéza
Cécile Berri
Amonrat Molee
Wittawat Molee
author_facet Piyaradtana Homyok
Wunpen Sonsamrong
Nitipol Chainet
Wichuta Khosinklang
Anyanee Kamkaew
Teerapong Yata
Elisabeth Baéza
Cécile Berri
Amonrat Molee
Wittawat Molee
author_sort Piyaradtana Homyok
collection DOAJ
description This research aimed to investigate the optimization of lipid-based nanoparticles to improve the utilization of n-3 PUFA source in chicken diets. Three groups of slow-growing Korat chickens were reared under the same conditions and fed a diet containing 6 % rice bran oil (RBO, control group), 3 % tuna oil (3 % TO) and 3 % tuna oil in targeted lipid-based nanoparticles (3 % TO-TNP). The growth performance, carcass composition, meat quality, fatty acid profile of breast and thigh meat, hematological and plasma biochemical parameters were evaluated. The dietary lipid source had no effect on the growth performance, carcass composition, or breast and thigh meat quality (P > 0.05). Compared to the control group, the 3 % TO and 3 % TO-TNP groups exhibited lower levels of C18:2n-6 (linoleic acid) and n-6 PUFA (P < 0.05). There was no significant difference between groups in the C18:3n-3 (ALA) level in breast and thigh meat, whereas the levels of C20:5n-3 (EPA) and C22:6n-3 (DHA) were higher in both TO groups. However, due to the high temperature required during the drying step of the nanoparticle synthesis process, n-3 PUFA enrichment was more efficient when TO was directly incorporated into the diet than when using targeted nanoparticles. Nevertheless, there was no difference between the 3 % TO and 3 % TO-TNP groups in the n-6/n-3 ratio (P > 0.05). The hemoglobin and hematocrit values were higher in 3 % TO-TNP than in the other groups (P < 0.05). In the plasma, HDL level was reduced in the TO groups compared to the control group (P < 0.05) suggesting a lower cholesterol hepatic synthesis and export. The TO groups had a higher activity of alanine amino transferase but a lower creatinine content than the control group (P < 0.05). The uric acid content was higher in 3 % TO-TNP group than in the 3 % TO group (P < 0.05) but no different compared with the control group. However, the values obtained for the hematological and biochemistry parameters measured in blood and plasma were within the normal range for chickens. To conclude, the supplementation of lipid-based nanoparticles allowed for change the fatty acid composition of chicken meat without any negative effect on production and health status of chickens.
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spelling doaj-art-bd1c20eb5beb4cf98035358467d47c302025-08-20T02:58:50ZengElsevierPoultry Science0032-57912025-04-01104410498210.1016/j.psj.2025.104982Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parametersPiyaradtana Homyok0Wunpen Sonsamrong1Nitipol Chainet2Wichuta Khosinklang3Anyanee Kamkaew4Teerapong Yata5Elisabeth Baéza6Cécile Berri7Amonrat Molee8Wittawat Molee9School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, ThailandSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, ThailandSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, ThailandSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, ThailandSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, ThailandBiochemistry Unit, Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandINRAE, Université de Tours, UMR BOA, 37380 Nouzilly, FranceINRAE, Université de Tours, UMR BOA, 37380 Nouzilly, FranceSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, ThailandSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, Thailand; Corresponding author.This research aimed to investigate the optimization of lipid-based nanoparticles to improve the utilization of n-3 PUFA source in chicken diets. Three groups of slow-growing Korat chickens were reared under the same conditions and fed a diet containing 6 % rice bran oil (RBO, control group), 3 % tuna oil (3 % TO) and 3 % tuna oil in targeted lipid-based nanoparticles (3 % TO-TNP). The growth performance, carcass composition, meat quality, fatty acid profile of breast and thigh meat, hematological and plasma biochemical parameters were evaluated. The dietary lipid source had no effect on the growth performance, carcass composition, or breast and thigh meat quality (P > 0.05). Compared to the control group, the 3 % TO and 3 % TO-TNP groups exhibited lower levels of C18:2n-6 (linoleic acid) and n-6 PUFA (P < 0.05). There was no significant difference between groups in the C18:3n-3 (ALA) level in breast and thigh meat, whereas the levels of C20:5n-3 (EPA) and C22:6n-3 (DHA) were higher in both TO groups. However, due to the high temperature required during the drying step of the nanoparticle synthesis process, n-3 PUFA enrichment was more efficient when TO was directly incorporated into the diet than when using targeted nanoparticles. Nevertheless, there was no difference between the 3 % TO and 3 % TO-TNP groups in the n-6/n-3 ratio (P > 0.05). The hemoglobin and hematocrit values were higher in 3 % TO-TNP than in the other groups (P < 0.05). In the plasma, HDL level was reduced in the TO groups compared to the control group (P < 0.05) suggesting a lower cholesterol hepatic synthesis and export. The TO groups had a higher activity of alanine amino transferase but a lower creatinine content than the control group (P < 0.05). The uric acid content was higher in 3 % TO-TNP group than in the 3 % TO group (P < 0.05) but no different compared with the control group. However, the values obtained for the hematological and biochemistry parameters measured in blood and plasma were within the normal range for chickens. To conclude, the supplementation of lipid-based nanoparticles allowed for change the fatty acid composition of chicken meat without any negative effect on production and health status of chickens.http://www.sciencedirect.com/science/article/pii/S0032579125002214n-3 PUFALipid-based nanoparticleSlow-growing chickenMeat qualityHealth status
spellingShingle Piyaradtana Homyok
Wunpen Sonsamrong
Nitipol Chainet
Wichuta Khosinklang
Anyanee Kamkaew
Teerapong Yata
Elisabeth Baéza
Cécile Berri
Amonrat Molee
Wittawat Molee
Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters
Poultry Science
n-3 PUFA
Lipid-based nanoparticle
Slow-growing chicken
Meat quality
Health status
title Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters
title_full Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters
title_fullStr Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters
title_full_unstemmed Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters
title_short Optimizing n-3 PUFA dietary enrichment in slow-growing Korat chickens using lipid-based nanoparticles: Effects on growth performance, carcass traits, meat quality, meat fatty acid composition, and blood biochemical parameters
title_sort optimizing n 3 pufa dietary enrichment in slow growing korat chickens using lipid based nanoparticles effects on growth performance carcass traits meat quality meat fatty acid composition and blood biochemical parameters
topic n-3 PUFA
Lipid-based nanoparticle
Slow-growing chicken
Meat quality
Health status
url http://www.sciencedirect.com/science/article/pii/S0032579125002214
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