Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate.

Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate.

Flaviviruses represent a significant global health threat and relatively few licensed vaccines exist to protect against them. Insect-specific flaviviruses (ISFVs) are incapable of replication in humans and have emerged as a novel and promising tool for flavivirus vaccine development. ISFV-based flav...

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Main Authors: Danielle L Porier, Awadalkareem Adam, Lin Kang, Pawel Michalak, Juselyn Tupik, Matthew A Santos, Manette Tanelus, Krisangel López, Dawn I Auguste, Christy Lee, Irving C Allen, Tian Wang, Albert J Auguste
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012566
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