Genetic risks of addictive disorders in adolescents: phenotypic effects
In several unrelated small samples examined correlation between genetic risk of chemical dependence, calculated on the basis of the contribution of geomarkers dopamine system, and phenotype of adolescents 14-17 years of age, not suffering from addiction. When genetic risk increases, the tendency to...
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| Format: | Article |
| Language: | Russian |
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Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
2019-12-01
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| Series: | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
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| Online Access: | https://www.bekhterevreview.com/jour/article/view/311 |
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| _version_ | 1849388949856845824 |
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| author | A. N. Yakovlev N. V. Pashkevich V. I. Vitchinkina |
| author_facet | A. N. Yakovlev N. V. Pashkevich V. I. Vitchinkina |
| author_sort | A. N. Yakovlev |
| collection | DOAJ |
| description | In several unrelated small samples examined correlation between genetic risk of chemical dependence, calculated on the basis of the contribution of geomarkers dopamine system, and phenotype of adolescents 14-17 years of age, not suffering from addiction. When genetic risk increases, the tendency to behavioural disorders increases, the tendency to abandon positive forms of self-assertion increases, the intensity of euphoria increases at the first drug samples, and the ability to predict the consequences of drug use decreases. The obtained correlations may be important for understanding the mechanism of dependence formation in adolescents with high genetic risk and development of individual prevention programs. However, these observations need to be confirmed in more representative studies. |
| format | Article |
| id | doaj-art-bd075d5cbbc44927abdf0a61cea82e13 |
| institution | Kabale University |
| issn | 2313-7053 2713-055X |
| language | Russian |
| publishDate | 2019-12-01 |
| publisher | Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation |
| record_format | Article |
| series | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| spelling | doaj-art-bd075d5cbbc44927abdf0a61cea82e132025-08-20T03:42:06ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2019-12-0104-1737410.31363/2313-7053-2019-4-1-73-7290Genetic risks of addictive disorders in adolescents: phenotypic effectsA. N. Yakovlev0N. V. Pashkevich1V. I. Vitchinkina2Lipetsk regional narcological dispensaryLipetsk regional narcological dispensaryLipetsk regional narcological dispensaryIn several unrelated small samples examined correlation between genetic risk of chemical dependence, calculated on the basis of the contribution of geomarkers dopamine system, and phenotype of adolescents 14-17 years of age, not suffering from addiction. When genetic risk increases, the tendency to behavioural disorders increases, the tendency to abandon positive forms of self-assertion increases, the intensity of euphoria increases at the first drug samples, and the ability to predict the consequences of drug use decreases. The obtained correlations may be important for understanding the mechanism of dependence formation in adolescents with high genetic risk and development of individual prevention programs. However, these observations need to be confirmed in more representative studies.https://www.bekhterevreview.com/jour/article/view/311dopamine, genetic risk, phenotype, alcohol, drug |
| spellingShingle | A. N. Yakovlev N. V. Pashkevich V. I. Vitchinkina Genetic risks of addictive disorders in adolescents: phenotypic effects Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева dopamine, genetic risk, phenotype, alcohol, drug |
| title | Genetic risks of addictive disorders in adolescents: phenotypic effects |
| title_full | Genetic risks of addictive disorders in adolescents: phenotypic effects |
| title_fullStr | Genetic risks of addictive disorders in adolescents: phenotypic effects |
| title_full_unstemmed | Genetic risks of addictive disorders in adolescents: phenotypic effects |
| title_short | Genetic risks of addictive disorders in adolescents: phenotypic effects |
| title_sort | genetic risks of addictive disorders in adolescents phenotypic effects |
| topic | dopamine, genetic risk, phenotype, alcohol, drug |
| url | https://www.bekhterevreview.com/jour/article/view/311 |
| work_keys_str_mv | AT anyakovlev geneticrisksofaddictivedisordersinadolescentsphenotypiceffects AT nvpashkevich geneticrisksofaddictivedisordersinadolescentsphenotypiceffects AT vivitchinkina geneticrisksofaddictivedisordersinadolescentsphenotypiceffects |