Genetic risks of addictive disorders in adolescents: phenotypic effects

In several unrelated small samples examined correlation between genetic risk of chemical dependence, calculated on the basis of the contribution of geomarkers dopamine system, and phenotype of adolescents 14-17 years of age, not suffering from addiction. When genetic risk increases, the tendency to...

Full description

Saved in:
Bibliographic Details
Main Authors: A. N. Yakovlev, N. V. Pashkevich, V. I. Vitchinkina
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2019-12-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
Subjects:
Online Access:https://www.bekhterevreview.com/jour/article/view/311
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In several unrelated small samples examined correlation between genetic risk of chemical dependence, calculated on the basis of the contribution of geomarkers dopamine system, and phenotype of adolescents 14-17 years of age, not suffering from addiction. When genetic risk increases, the tendency to behavioural disorders increases, the tendency to abandon positive forms of self-assertion increases, the intensity of euphoria increases at the first drug samples, and the ability to predict the consequences of drug use decreases. The obtained correlations may be important for understanding the mechanism of dependence formation in adolescents with high genetic risk and development of individual prevention programs. However, these observations need to be confirmed in more representative studies.
ISSN:2313-7053
2713-055X