Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy
Purpose. To characterize vitelliform lesions (VLs) in adult-onset foveomacular vitelliform dystrophy (AOFVD) and acquired vitelliform (AVL) patients using multimodal image analysis. Methods. Retrospective study of twenty-eight eyes from nineteen patients diagnosed with AVL or AOFVD. They were evalua...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/6037537 |
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| author | Ricardo Rocha Bastos Carla Sofia Ferreira Elisete Brandão Fernando Falcão-Reis Ângela M. Carneiro |
| author_facet | Ricardo Rocha Bastos Carla Sofia Ferreira Elisete Brandão Fernando Falcão-Reis Ângela M. Carneiro |
| author_sort | Ricardo Rocha Bastos |
| collection | DOAJ |
| description | Purpose. To characterize vitelliform lesions (VLs) in adult-onset foveomacular vitelliform dystrophy (AOFVD) and acquired vitelliform (AVL) patients using multimodal image analysis. Methods. Retrospective study of twenty-eight eyes from nineteen patients diagnosed with AVL or AOFVD. They were evaluated by color fundus photographs, fundus autofluorescence (FAF), fluorescein angiography (FA), and spectral-domain optical coherence tomography (SD-OCT). Results. Bilateral VLs were associated with AOFVD (p=0.013). Regular and centered VLs were associated with AOFVD (p=0.004 and p=0.016), whereas irregular and noncentered lesions were more frequent in AVL patients. Visual acuity, greatest linear dimension (GLD), lesion height (LH), and pseudohypopyon were similar between groups. Whereas median LH and GLD in AVL group diminished significantly during follow-up (p=0.009 and p=0.001), AOFVD lesions tended to become larger and thicker. Conclusions. When consulting a patient presenting a VL with unknown age of onset, familial history, or previous retinal diseases, some aspects of multimodal imaging assessment may lead the ophthalmologist to a correct diagnosis. |
| format | Article |
| id | doaj-art-bd060ed94b9942d5961485ac105236e4 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-bd060ed94b9942d5961485ac105236e42025-02-03T07:23:50ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/60375376037537Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform DystrophyRicardo Rocha Bastos0Carla Sofia Ferreira1Elisete Brandão2Fernando Falcão-Reis3Ângela M. Carneiro4Department of Ophthalmology, Hospital São João, Porto, PortugalDepartment of Ophthalmology, Hospital São João, Porto, PortugalDepartment of Ophthalmology, Hospital São João, Porto, PortugalDepartment of Ophthalmology, Hospital São João, Porto, PortugalDepartment of Ophthalmology, Hospital São João, Porto, PortugalPurpose. To characterize vitelliform lesions (VLs) in adult-onset foveomacular vitelliform dystrophy (AOFVD) and acquired vitelliform (AVL) patients using multimodal image analysis. Methods. Retrospective study of twenty-eight eyes from nineteen patients diagnosed with AVL or AOFVD. They were evaluated by color fundus photographs, fundus autofluorescence (FAF), fluorescein angiography (FA), and spectral-domain optical coherence tomography (SD-OCT). Results. Bilateral VLs were associated with AOFVD (p=0.013). Regular and centered VLs were associated with AOFVD (p=0.004 and p=0.016), whereas irregular and noncentered lesions were more frequent in AVL patients. Visual acuity, greatest linear dimension (GLD), lesion height (LH), and pseudohypopyon were similar between groups. Whereas median LH and GLD in AVL group diminished significantly during follow-up (p=0.009 and p=0.001), AOFVD lesions tended to become larger and thicker. Conclusions. When consulting a patient presenting a VL with unknown age of onset, familial history, or previous retinal diseases, some aspects of multimodal imaging assessment may lead the ophthalmologist to a correct diagnosis.http://dx.doi.org/10.1155/2016/6037537 |
| spellingShingle | Ricardo Rocha Bastos Carla Sofia Ferreira Elisete Brandão Fernando Falcão-Reis Ângela M. Carneiro Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy Journal of Ophthalmology |
| title | Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy |
| title_full | Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy |
| title_fullStr | Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy |
| title_full_unstemmed | Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy |
| title_short | Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy |
| title_sort | multimodal image analysis in acquired vitelliform lesions and adult onset foveomacular vitelliform dystrophy |
| url | http://dx.doi.org/10.1155/2016/6037537 |
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