Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
Hospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore,...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2020-09-01
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| Series: | Cardiac Failure Review |
| Online Access: | https://www.cfrjournal.com/articles/congestion-and-diuretic-resistance |
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| author | Ingibjörg Kristjánsdóttir Tonje Thorvaldsen Lars H Lund |
| author_facet | Ingibjörg Kristjánsdóttir Tonje Thorvaldsen Lars H Lund |
| author_sort | Ingibjörg Kristjánsdóttir |
| collection | DOAJ |
| description | Hospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore, decongestion is the number one treatment goal. Diuretics are the cornerstone of therapy in AHF, but the treatment effect is challenged by diuretic resistance and poor diuretic response throughout the spectrum of chronic to worsening to acute to post-worsening HF. Adequate dosing and monitoring and evaluation of diuretic effect are important for treatment success. Residual congestion at discharge is a strong predictor of worse outcomes. Therefore, achieving euvolaemia is crucial despite transient worsening renal function. |
| format | Article |
| id | doaj-art-bd035d6b11864aefbe57fc70c6d15d67 |
| institution | OA Journals |
| issn | 2057-7540 2057-7559 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Cardiac Failure Review |
| spelling | doaj-art-bd035d6b11864aefbe57fc70c6d15d672025-08-20T02:37:48ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592020-09-01610.15420/cfr.2019.18Congestion and Diuretic Resistance in Acute or Worsening Heart FailureIngibjörg Kristjánsdóttir0Tonje Thorvaldsen1Lars H Lund2Karolinska Institutet, Department of Medicine, Stockholm, Sweden; and Karolinska University Hospital, Heart and Vascular Theme, Stockholm, SwedenKarolinska Institutet, Department of Medicine, Stockholm, Sweden; and Karolinska University Hospital, Heart and Vascular Theme, Stockholm, SwedenKarolinska Institutet, Department of Medicine, Stockholm, Sweden; and Karolinska University Hospital, Heart and Vascular Theme, Stockholm, SwedenHospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore, decongestion is the number one treatment goal. Diuretics are the cornerstone of therapy in AHF, but the treatment effect is challenged by diuretic resistance and poor diuretic response throughout the spectrum of chronic to worsening to acute to post-worsening HF. Adequate dosing and monitoring and evaluation of diuretic effect are important for treatment success. Residual congestion at discharge is a strong predictor of worse outcomes. Therefore, achieving euvolaemia is crucial despite transient worsening renal function.https://www.cfrjournal.com/articles/congestion-and-diuretic-resistance |
| spellingShingle | Ingibjörg Kristjánsdóttir Tonje Thorvaldsen Lars H Lund Congestion and Diuretic Resistance in Acute or Worsening Heart Failure Cardiac Failure Review |
| title | Congestion and Diuretic Resistance in Acute or Worsening Heart Failure |
| title_full | Congestion and Diuretic Resistance in Acute or Worsening Heart Failure |
| title_fullStr | Congestion and Diuretic Resistance in Acute or Worsening Heart Failure |
| title_full_unstemmed | Congestion and Diuretic Resistance in Acute or Worsening Heart Failure |
| title_short | Congestion and Diuretic Resistance in Acute or Worsening Heart Failure |
| title_sort | congestion and diuretic resistance in acute or worsening heart failure |
| url | https://www.cfrjournal.com/articles/congestion-and-diuretic-resistance |
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