A Review on Fucoidan Extraction, Degradation, and Bioactivity

The ocean is a treasure trove of natural polymers with diverse chemical structures and biological activities, among which polysaccharides represent one of the most abundant marine resources. Fucoidan, derived from brown algae, possesses significant biological activities, including antioxidant, anti-...

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Main Authors: Yanni LI, Yijin CAI, Ziteng WANG, Yadong HU, Mingxuan PAN, Wenge YANG, Xinghu ZHOU, Yonghong HU
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2025-07-01
Series:Shipin gongye ke-ji
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Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024060396
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author Yanni LI
Yijin CAI
Ziteng WANG
Yadong HU
Mingxuan PAN
Wenge YANG
Xinghu ZHOU
Yonghong HU
author_facet Yanni LI
Yijin CAI
Ziteng WANG
Yadong HU
Mingxuan PAN
Wenge YANG
Xinghu ZHOU
Yonghong HU
author_sort Yanni LI
collection DOAJ
description The ocean is a treasure trove of natural polymers with diverse chemical structures and biological activities, among which polysaccharides represent one of the most abundant marine resources. Fucoidan, derived from brown algae, possesses significant biological activities, including antioxidant, anti-tumor, immune-boosting, liver and kidney function-improving, and blood sugar-regulating effects. It has unique application values in food, medicine, and materials. Compared with natural fucoidan, low molecular weight fucoidan has higher water solubility and bioavailability, and stronger prebiotic activity, which has attracted much attention. This paper reviews the structure, extraction, purification, and degradation methods for the preparation of low molecular weight fucoidan, and summarizes and prospects the biological activity of low molecular weight fucoidan, which provides a theoretical basis for further study and a reference for the high-value development and utilization of marine algae resources.
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publisher The editorial department of Science and Technology of Food Industry
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series Shipin gongye ke-ji
spelling doaj-art-bcfcae7b752244d8b68ca1fb5a75810e2025-08-20T03:16:17ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062025-07-01461338339410.13386/j.issn1002-0306.20240603962024060396-13A Review on Fucoidan Extraction, Degradation, and BioactivityYanni LI0Yijin CAI1Ziteng WANG2Yadong HU3Mingxuan PAN4Wenge YANG5Xinghu ZHOU6Yonghong HU7College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, ChinaCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, ChinaCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, ChinaJiangsu Coast Development Investment Co., Ltd., Nanjing 210019, ChinaJiangsu Coast Development Investment Co., Ltd., Nanjing 210019, ChinaSchool of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, ChinaJiangsu Coast Development Investment Co., Ltd., Nanjing 210019, ChinaCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, ChinaThe ocean is a treasure trove of natural polymers with diverse chemical structures and biological activities, among which polysaccharides represent one of the most abundant marine resources. Fucoidan, derived from brown algae, possesses significant biological activities, including antioxidant, anti-tumor, immune-boosting, liver and kidney function-improving, and blood sugar-regulating effects. It has unique application values in food, medicine, and materials. Compared with natural fucoidan, low molecular weight fucoidan has higher water solubility and bioavailability, and stronger prebiotic activity, which has attracted much attention. This paper reviews the structure, extraction, purification, and degradation methods for the preparation of low molecular weight fucoidan, and summarizes and prospects the biological activity of low molecular weight fucoidan, which provides a theoretical basis for further study and a reference for the high-value development and utilization of marine algae resources.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024060396fucoidanpreparation of low molecular weight fucoidanfucoidanasesimmunoenhancing activityanti-cancer activity
spellingShingle Yanni LI
Yijin CAI
Ziteng WANG
Yadong HU
Mingxuan PAN
Wenge YANG
Xinghu ZHOU
Yonghong HU
A Review on Fucoidan Extraction, Degradation, and Bioactivity
Shipin gongye ke-ji
fucoidan
preparation of low molecular weight fucoidan
fucoidanases
immunoenhancing activity
anti-cancer activity
title A Review on Fucoidan Extraction, Degradation, and Bioactivity
title_full A Review on Fucoidan Extraction, Degradation, and Bioactivity
title_fullStr A Review on Fucoidan Extraction, Degradation, and Bioactivity
title_full_unstemmed A Review on Fucoidan Extraction, Degradation, and Bioactivity
title_short A Review on Fucoidan Extraction, Degradation, and Bioactivity
title_sort review on fucoidan extraction degradation and bioactivity
topic fucoidan
preparation of low molecular weight fucoidan
fucoidanases
immunoenhancing activity
anti-cancer activity
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024060396
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