Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells

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Main Authors: Jie Guo, Wen-Long Peng, Chen-Guang Li, Yu-Long Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1583920/full
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author Jie Guo
Wen-Long Peng
Chen-Guang Li
Yu-Long Wang
author_facet Jie Guo
Wen-Long Peng
Chen-Guang Li
Yu-Long Wang
author_sort Jie Guo
collection DOAJ
format Article
id doaj-art-bcf9527c5540420e9acfeebce7939da9
institution OA Journals
issn 1663-9812
language English
publishDate 2025-04-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj-art-bcf9527c5540420e9acfeebce7939da92025-08-20T02:19:16ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-04-011610.3389/fphar.2025.15839201583920Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cellsJie Guo0Wen-Long Peng1Chen-Guang Li2Yu-Long Wang3Department of Rehabilitation Medicine, Shenzhen Second People’s Hospital, Shenzhen, ChinaDepartment of Rehabilitation Medicine, Shenzhen Second People’s Hospital, Shenzhen, ChinaPain Department of Shenzhen Nanshan People’s Hospital, Shenzhen, ChinaDepartment of Rehabilitation Medicine, Shenzhen Second People’s Hospital, Shenzhen, Chinahttps://www.frontiersin.org/articles/10.3389/fphar.2025.1583920/fullMCF-7 cellsgasdermin Ecaspase-3pyroptosisbreast cancer
spellingShingle Jie Guo
Wen-Long Peng
Chen-Guang Li
Yu-Long Wang
Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells
Frontiers in Pharmacology
MCF-7 cells
gasdermin E
caspase-3
pyroptosis
breast cancer
title Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells
title_full Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells
title_fullStr Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells
title_full_unstemmed Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells
title_short Commentary: Triclabendazole induces pyroptosis by activating caspase-3 to cleave GSDME in breast cancer cells
title_sort commentary triclabendazole induces pyroptosis by activating caspase 3 to cleave gsdme in breast cancer cells
topic MCF-7 cells
gasdermin E
caspase-3
pyroptosis
breast cancer
url https://www.frontiersin.org/articles/10.3389/fphar.2025.1583920/full
work_keys_str_mv AT jieguo commentarytriclabendazoleinducespyroptosisbyactivatingcaspase3tocleavegsdmeinbreastcancercells
AT wenlongpeng commentarytriclabendazoleinducespyroptosisbyactivatingcaspase3tocleavegsdmeinbreastcancercells
AT chenguangli commentarytriclabendazoleinducespyroptosisbyactivatingcaspase3tocleavegsdmeinbreastcancercells
AT yulongwang commentarytriclabendazoleinducespyroptosisbyactivatingcaspase3tocleavegsdmeinbreastcancercells