Gambogenic Acid Suppresses Malignant Progression of Non-Small Cell Lung Cancer via GCH1-Mediated Ferroptosis

Gambogenic Acid Suppresses Malignant Progression of Non-Small Cell Lung Cancer via GCH1-Mediated Ferroptosis

<b>Introduction:</b> Non-small cell lung cancer (NSCLC) is a lethal type of lung cancer (LC) with a 5-year survival rate of 19%. Because drug resistance typically develops following chemotherapy, radiotherapy, and immunotherapy, a novel NSCLC therapeutic strategy is urgently demanded. Ga...

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Bibliographic Details
Main Authors: Menghan Wang, Jiao Liu, Wenxi Yu, Jiancang Shao, Yang Bao, Mingming Jin, Qingqing Huang, Gang Huang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
gambogenic acid
non-small cell lung cancer
ferroptosis
GCH1
Online Access:https://www.mdpi.com/1424-8247/18/3/374
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