Research Progress on Chitinase and Chitosanase with Transglycosylation Activity
N−acetyl chitooligosaccharides and chitooligosaccharides with high degree of polymerization are highly valued for their superior bioactivities. However, traditional preparation methods face various limitations, such as uncontrollable processes and challenges inseparation and purification. Recent stu...
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| Format: | Article |
| Language: | zho |
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The editorial department of Science and Technology of Food Industry
2025-07-01
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| Series: | Shipin gongye ke-ji |
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| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024070134 |
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| _version_ | 1849683355908440064 |
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| author | Yingying WEI Minjuan GUI Huihui SUN Ling ZHAO Rong CAO |
| author_facet | Yingying WEI Minjuan GUI Huihui SUN Ling ZHAO Rong CAO |
| author_sort | Yingying WEI |
| collection | DOAJ |
| description | N−acetyl chitooligosaccharides and chitooligosaccharides with high degree of polymerization are highly valued for their superior bioactivities. However, traditional preparation methods face various limitations, such as uncontrollable processes and challenges inseparation and purification. Recent studies have discovered that certain chitinases and chitosanases possess both hydrolysis and transglycosylation (TG) activities. The TG reaction offers advantages in producing oligosaccharides with high-degree polymerization, including easy accessibility to substrates and low production costs. This paper reviews recent advances in chitinases and chitosanases with TG activity, analyzes the key amino acid residues affecting TG activity in chitinases, and discusses the impact of molecular modifications of these key residues on TG activity. The goal is to provide insights for further research on chitinases and chitosanases with TG activity and their subsequent development and utilization, thereby promoting the green production and industrialization of oligosaccharides with high-degree polymerization. |
| format | Article |
| id | doaj-art-bcf56cc0d4894c2bb5f4312c35baaa7a |
| institution | DOAJ |
| issn | 1002-0306 |
| language | zho |
| publishDate | 2025-07-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj-art-bcf56cc0d4894c2bb5f4312c35baaa7a2025-08-20T03:23:56ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062025-07-01461340441210.13386/j.issn1002-0306.20240701342024070134-13Research Progress on Chitinase and Chitosanase with Transglycosylation ActivityYingying WEI0Minjuan GUI1Huihui SUN2Ling ZHAO3Rong CAO4College of Food Science and Engineering, Ocean University of China, Qingdao 266404, ChinaCollege of Food Science and Engineering, Ocean University of China, Qingdao 266404, ChinaYellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, ChinaYellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, ChinaYellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, ChinaN−acetyl chitooligosaccharides and chitooligosaccharides with high degree of polymerization are highly valued for their superior bioactivities. However, traditional preparation methods face various limitations, such as uncontrollable processes and challenges inseparation and purification. Recent studies have discovered that certain chitinases and chitosanases possess both hydrolysis and transglycosylation (TG) activities. The TG reaction offers advantages in producing oligosaccharides with high-degree polymerization, including easy accessibility to substrates and low production costs. This paper reviews recent advances in chitinases and chitosanases with TG activity, analyzes the key amino acid residues affecting TG activity in chitinases, and discusses the impact of molecular modifications of these key residues on TG activity. The goal is to provide insights for further research on chitinases and chitosanases with TG activity and their subsequent development and utilization, thereby promoting the green production and industrialization of oligosaccharides with high-degree polymerization.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024070134transglycosylation activitychitinasechitosanasehigh deep of polymerizationmolecular modification |
| spellingShingle | Yingying WEI Minjuan GUI Huihui SUN Ling ZHAO Rong CAO Research Progress on Chitinase and Chitosanase with Transglycosylation Activity Shipin gongye ke-ji transglycosylation activity chitinase chitosanase high deep of polymerization molecular modification |
| title | Research Progress on Chitinase and Chitosanase with Transglycosylation Activity |
| title_full | Research Progress on Chitinase and Chitosanase with Transglycosylation Activity |
| title_fullStr | Research Progress on Chitinase and Chitosanase with Transglycosylation Activity |
| title_full_unstemmed | Research Progress on Chitinase and Chitosanase with Transglycosylation Activity |
| title_short | Research Progress on Chitinase and Chitosanase with Transglycosylation Activity |
| title_sort | research progress on chitinase and chitosanase with transglycosylation activity |
| topic | transglycosylation activity chitinase chitosanase high deep of polymerization molecular modification |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024070134 |
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