The role and prospects of skin microbiota in dermatosis
The skin microbiota is crucial in defending against toxic, solar, and pathogenic assaults, yet it can also precipitate dermatosis when its equilibrium is disrupted. The composition and distribution of various microorganisms within the skin maintain a dynamic balance, modulating the barrier function...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-06-01
|
| Series: | Therapeutic Advances in Infectious Disease |
| Online Access: | https://doi.org/10.1177/20499361251333562 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850102426915307520 |
|---|---|
| author | Yuanyuan Chen Zhijian Yao Zhuren Ruan Gao Wei Wenjun Zheng Xianghui Li |
| author_facet | Yuanyuan Chen Zhijian Yao Zhuren Ruan Gao Wei Wenjun Zheng Xianghui Li |
| author_sort | Yuanyuan Chen |
| collection | DOAJ |
| description | The skin microbiota is crucial in defending against toxic, solar, and pathogenic assaults, yet it can also precipitate dermatosis when its equilibrium is disrupted. The composition and distribution of various microorganisms within the skin maintain a dynamic balance, modulating the barrier function and the immune system, thereby constituting the skin microbiota. This microbiota not only offers new insights into pathological microbe-host interactions and associated dermatoses but also inspires innovative therapeutic strategies that promise high efficacy and reduced symptomatology. In this review, we synthesize recent advancements in the field of skin microbiota, focusing on its relationship with dermatosis and the application of microbiota-based therapies in skin diseases. Our aim is to scrutinize the current understanding of the skin microbiota’s role, ranging from a protective barrier to a causative agent of dermatosis. |
| format | Article |
| id | doaj-art-bcf368826cc24acbb8fc054b8fbc805c |
| institution | DOAJ |
| issn | 2049-937X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Infectious Disease |
| spelling | doaj-art-bcf368826cc24acbb8fc054b8fbc805c2025-08-20T02:39:44ZengSAGE PublishingTherapeutic Advances in Infectious Disease2049-937X2025-06-011210.1177/20499361251333562The role and prospects of skin microbiota in dermatosisYuanyuan ChenZhijian YaoZhuren RuanGao WeiWenjun ZhengXianghui LiThe skin microbiota is crucial in defending against toxic, solar, and pathogenic assaults, yet it can also precipitate dermatosis when its equilibrium is disrupted. The composition and distribution of various microorganisms within the skin maintain a dynamic balance, modulating the barrier function and the immune system, thereby constituting the skin microbiota. This microbiota not only offers new insights into pathological microbe-host interactions and associated dermatoses but also inspires innovative therapeutic strategies that promise high efficacy and reduced symptomatology. In this review, we synthesize recent advancements in the field of skin microbiota, focusing on its relationship with dermatosis and the application of microbiota-based therapies in skin diseases. Our aim is to scrutinize the current understanding of the skin microbiota’s role, ranging from a protective barrier to a causative agent of dermatosis.https://doi.org/10.1177/20499361251333562 |
| spellingShingle | Yuanyuan Chen Zhijian Yao Zhuren Ruan Gao Wei Wenjun Zheng Xianghui Li The role and prospects of skin microbiota in dermatosis Therapeutic Advances in Infectious Disease |
| title | The role and prospects of skin microbiota in dermatosis |
| title_full | The role and prospects of skin microbiota in dermatosis |
| title_fullStr | The role and prospects of skin microbiota in dermatosis |
| title_full_unstemmed | The role and prospects of skin microbiota in dermatosis |
| title_short | The role and prospects of skin microbiota in dermatosis |
| title_sort | role and prospects of skin microbiota in dermatosis |
| url | https://doi.org/10.1177/20499361251333562 |
| work_keys_str_mv | AT yuanyuanchen theroleandprospectsofskinmicrobiotaindermatosis AT zhijianyao theroleandprospectsofskinmicrobiotaindermatosis AT zhurenruan theroleandprospectsofskinmicrobiotaindermatosis AT gaowei theroleandprospectsofskinmicrobiotaindermatosis AT wenjunzheng theroleandprospectsofskinmicrobiotaindermatosis AT xianghuili theroleandprospectsofskinmicrobiotaindermatosis AT yuanyuanchen roleandprospectsofskinmicrobiotaindermatosis AT zhijianyao roleandprospectsofskinmicrobiotaindermatosis AT zhurenruan roleandprospectsofskinmicrobiotaindermatosis AT gaowei roleandprospectsofskinmicrobiotaindermatosis AT wenjunzheng roleandprospectsofskinmicrobiotaindermatosis AT xianghuili roleandprospectsofskinmicrobiotaindermatosis |