3D transcranial ultrasound localization microscopy in awake mice: protocol and open-source pipeline

3D transcranial ultrasound localization microscopy in awake mice: protocol and open-source pipeline

Abstract We present an open-source code for 3D super-resolution ultrasound imaging. Open-3DULM was applied to transcranial imaging in habituated awake mice. Comparative analysis reveals that isoflurane anesthesia induces significant vasodilation and increased cerebral blood flow (CBF) in veins, whil...

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Main Authors: Georges Chabouh, Louise Denis, Myriam Abioui-Mourgues, Jean-Baptiste Deloges, Jacques Battaglia, Arthur Chavignon, Baptiste Heiles, Basile Pradier, Sylvain Bodard, Denis Vivien, Cyrille Orset, Olivier Couture
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Engineering
Online Access:https://doi.org/10.1038/s44172-025-00415-4
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