Dose dependent relationship of metformin use and diabetic peripheral neuropathy risk in patients with type 2 diabetes mellitus

Dose dependent relationship of metformin use and diabetic peripheral neuropathy risk in patients with type 2 diabetes mellitus

Abstract This study investigated the correlation between metformin use and diabetic peripheral neuropathy (DPN) risk in patients with type 2 diabetes mellitus (T2DM) and its dose-dependent relationship. The study included new-onset T2DM patients from 2002 to 2013. Patients were divided into two grou...

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Bibliographic Details
Main Authors: Kuang-Hua Huang, Shiang-Wen Huang, Yih Yang, Shuo-Yan Gau, Tung-Han Tsai, Ya-Lan Chang, Chien-Ying Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Diabetes mellitus
Diabetic peripheral neuropathy
Metformin
Cumulative defined daily dose
Risk factors
Online Access:https://doi.org/10.1038/s41598-025-96445-1
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