Number of Doses of Systemic Antibiotic Prophylaxis May Be Reduced in Cemented Primary Knee Arthroplasty Irrespective of Use of Antibiotic in the Cement: A Multiregistry-Based Meta-Analysis

Number of Doses of Systemic Antibiotic Prophylaxis May Be Reduced in Cemented Primary Knee Arthroplasty Irrespective of Use of Antibiotic in the Cement: A Multiregistry-Based Meta-Analysis

Background:. The use of systemic antibiotic prophylaxis (SAP) and antibiotic-loaded bone cement (ALBC) is the accepted practice to reduce the risk of periprosthetic joint infection (PJI) in primary total knee arthroplasty (pTKA). However, practice varies internationally. This study's primary ai...

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Main Authors: Tesfaye H. Leta, PhD, Richard N. Chang, MPH, Anne Marie Fenstad, MSc, Stein Atle Lie, PhD, Stein Håkon L. Lygre, PhD, Martin Lindberg-Larsen, PhD, Alma B. Pedersen, PhD, Olav Lutro, MD, Jinny Willis, PhD, Chris Frampton, PhD, Michael Wyatt, MD, Serban Dragosloveanu, MD, Andreea E. Vorovenci, MSc, Dan Dragomirescu, MSc, Håvard Dale, PhD, Geir Hallan, PhD, Jan-Erik Gjertsen, PhD, Heather A. Prentice, PhD, Ove Furnes, PhD, Art Sedrakyan, PhD, Elizabeth W. Paxton, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2024-12-01
Series:JBJS Open Access
Online Access:http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.24.00140
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