Role of Kindlin-2-Expressing Extracellular Vesicles in the Invasiveness of Triple Negative Breast Cancer Tumor Cells

Role of Kindlin-2-Expressing Extracellular Vesicles in the Invasiveness of Triple Negative Breast Cancer Tumor Cells

Metastatic breast cancer (BC) is a major cause of cancer-related deaths among women. Its progression is influenced by extracellular vesicles (EVs) released by BC cells, which modulate distant tissue environments to promote metastasis. We previously identified the oncogenic protein Kindlin-2 (K2) as...

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Bibliographic Details
Main Authors: Neelum Aziz Yousafzai, Mark F. Santos, Yeaji Kim, Nofar Avihen Schahaf, Kim Zielke, Lucia Languino, Khalid Sossey-Alaoui, Aurelio Lorico
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
breast cancer
metastasis
extracellular vesicles
exosomes
kindlin
nucleus
Online Access:https://www.mdpi.com/2073-4409/14/13/1034
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