Early-onset Unilateral Terrien’s Marginal Degeneration

Purpose: We aimed to describe the cases that highlight the fact that Terrien’s marginal degeneration (TMD) can present at an early age and should be considered when evaluating young patients with peripheral corneal thinning disorders. Materials and Methods: All cases of early-onset unilateral TMD th...

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Main Authors: Sohini Mandal, Muskan Garg, Gaurav Sachdeva, Anushka Agarwalla, Prafulla Kumar Maharana
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-07-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/DLJO.DLJO_115_23
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author Sohini Mandal
Muskan Garg
Gaurav Sachdeva
Anushka Agarwalla
Prafulla Kumar Maharana
author_facet Sohini Mandal
Muskan Garg
Gaurav Sachdeva
Anushka Agarwalla
Prafulla Kumar Maharana
author_sort Sohini Mandal
collection DOAJ
description Purpose: We aimed to describe the cases that highlight the fact that Terrien’s marginal degeneration (TMD) can present at an early age and should be considered when evaluating young patients with peripheral corneal thinning disorders. Materials and Methods: All cases of early-onset unilateral TMD that presented to a tertiary eye care center were included in the study. Three cases of early-onset unilateral TMD were reviewed. Case 1 (10 years, male) presented with superior arcuate band of corneal stromal thinning extending from 9 to 3 o’clock hours. in the right eye with associated corneal vascularization and lipid deposition at the leading edge of the furrow. Case 2 (14 years, female) presented with a superior crescentic band of corneal stromal thinning extending from 10 to 2 o’clock positions in the left eye. Vascularization of the cornea and lipid deposition were observed at the leading edge of the furrow in this case as well. Case 3 (9 years, male) presented with a superior arcuate band of corneal stromal thinning extending from 10 to 2 o’clock positions in his left eye. Corneal vascularization and lipid deposition were observed at the leading edge of the furrow formation. Results: A preliminary diagnosis of early-onset unilateral TMD was made in all the cases that was subsequently confirmed on Scheimpflug imaging and anterior segment optical coherence tomography. The mean astigmatism of the affected eye was 4.6 ± 2.3 D. All cases were prescribed spectacle correction, which resulted in significant improvement: 6/60-6/24 (Case 1), 6/36-6/9 (Case 2), and 6/18-6/9 (Case 3). Conclusion: A comprehensive case history and meticulous slit-lamp examination are essential, and TMD should be considered a differential diagnosis for peripheral corneal ectatic disorders in childhood.
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spelling doaj-art-bccb92063303426e811b3625e22b5dc22025-08-20T01:47:38ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842023-07-0133319119410.4103/DLJO.DLJO_115_23Early-onset Unilateral Terrien’s Marginal DegenerationSohini MandalMuskan GargGaurav SachdevaAnushka AgarwallaPrafulla Kumar MaharanaPurpose: We aimed to describe the cases that highlight the fact that Terrien’s marginal degeneration (TMD) can present at an early age and should be considered when evaluating young patients with peripheral corneal thinning disorders. Materials and Methods: All cases of early-onset unilateral TMD that presented to a tertiary eye care center were included in the study. Three cases of early-onset unilateral TMD were reviewed. Case 1 (10 years, male) presented with superior arcuate band of corneal stromal thinning extending from 9 to 3 o’clock hours. in the right eye with associated corneal vascularization and lipid deposition at the leading edge of the furrow. Case 2 (14 years, female) presented with a superior crescentic band of corneal stromal thinning extending from 10 to 2 o’clock positions in the left eye. Vascularization of the cornea and lipid deposition were observed at the leading edge of the furrow in this case as well. Case 3 (9 years, male) presented with a superior arcuate band of corneal stromal thinning extending from 10 to 2 o’clock positions in his left eye. Corneal vascularization and lipid deposition were observed at the leading edge of the furrow formation. Results: A preliminary diagnosis of early-onset unilateral TMD was made in all the cases that was subsequently confirmed on Scheimpflug imaging and anterior segment optical coherence tomography. The mean astigmatism of the affected eye was 4.6 ± 2.3 D. All cases were prescribed spectacle correction, which resulted in significant improvement: 6/60-6/24 (Case 1), 6/36-6/9 (Case 2), and 6/18-6/9 (Case 3). Conclusion: A comprehensive case history and meticulous slit-lamp examination are essential, and TMD should be considered a differential diagnosis for peripheral corneal ectatic disorders in childhood.https://journals.lww.com/10.4103/DLJO.DLJO_115_23amblyopiaectatic disorders of childhoodreverse crab clawterrien’s marginal degeneration
spellingShingle Sohini Mandal
Muskan Garg
Gaurav Sachdeva
Anushka Agarwalla
Prafulla Kumar Maharana
Early-onset Unilateral Terrien’s Marginal Degeneration
Delhi Journal of Ophthalmology
amblyopia
ectatic disorders of childhood
reverse crab claw
terrien’s marginal degeneration
title Early-onset Unilateral Terrien’s Marginal Degeneration
title_full Early-onset Unilateral Terrien’s Marginal Degeneration
title_fullStr Early-onset Unilateral Terrien’s Marginal Degeneration
title_full_unstemmed Early-onset Unilateral Terrien’s Marginal Degeneration
title_short Early-onset Unilateral Terrien’s Marginal Degeneration
title_sort early onset unilateral terrien s marginal degeneration
topic amblyopia
ectatic disorders of childhood
reverse crab claw
terrien’s marginal degeneration
url https://journals.lww.com/10.4103/DLJO.DLJO_115_23
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AT muskangarg earlyonsetunilateralterriensmarginaldegeneration
AT gauravsachdeva earlyonsetunilateralterriensmarginaldegeneration
AT anushkaagarwalla earlyonsetunilateralterriensmarginaldegeneration
AT prafullakumarmaharana earlyonsetunilateralterriensmarginaldegeneration