First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy

A 69-year-old male patient, with bilateral hypoacusia and tinnitus, had a diagnosis of left vestibular schwannoma with synchronous meningioma on the left frontal lobe. After partial surgical resection of the acoustic schwannoma, this was followed by stereotactic radiosurgery on the residual lesion....

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Main Authors: Demetrio Arico, Claudio Giardina, Carmelo Tuscano, Antonio Picone, Vincenzo Militano
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2019-01-01
Series:World Journal of Nuclear Medicine
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Online Access:http://www.wjnm.org/article.asp?issn=1450-1147;year=2019;volume=18;issue=2;spage=187;epage=188;aulast=Arico
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author Demetrio Arico
Claudio Giardina
Carmelo Tuscano
Antonio Picone
Vincenzo Militano
author_facet Demetrio Arico
Claudio Giardina
Carmelo Tuscano
Antonio Picone
Vincenzo Militano
author_sort Demetrio Arico
collection DOAJ
description A 69-year-old male patient, with bilateral hypoacusia and tinnitus, had a diagnosis of left vestibular schwannoma with synchronous meningioma on the left frontal lobe. After partial surgical resection of the acoustic schwannoma, this was followed by stereotactic radiosurgery on the residual lesion. The patient had a metachronous prostate cancer treated with conformal radiotherapy associated to 6 months of hormone therapy with luteinizing hormone/releasing hormone analog. During follow-up, prostate-specific antigen value increased to 0.27 ng/mL and the patient underwent 18F-methylcholine positron emission tomography/computed tomography (18F-choline PET/CT). The whole-body scan demonstrated a focus of increased uptake at level of the left cerebellopontine angle and at the left frontal lobe, corresponding to the known vestibular schwannoma and meningioma. A subsequent brain contrast-enhanced magnetic resonance imaging (MRI) showed an increased dimension of the left cerebellopontine neuroma and dimensional stability of the left frontal meningioma compared with previous MRI of 6 months earlier. To the best of our knowledge, we describe the first case of a 18F-choline PET/CT demonstrating a relapse of a vestibular schwannoma after stereotactic radiotherapy.
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spelling doaj-art-bcc40bfd26fe4fbe9f90a0f78705cfe92025-08-20T02:54:43ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11472019-01-0118218718810.4103/wjnm.WJNM_26_18First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapyDemetrio AricoClaudio GiardinaCarmelo TuscanoAntonio PiconeVincenzo MilitanoA 69-year-old male patient, with bilateral hypoacusia and tinnitus, had a diagnosis of left vestibular schwannoma with synchronous meningioma on the left frontal lobe. After partial surgical resection of the acoustic schwannoma, this was followed by stereotactic radiosurgery on the residual lesion. The patient had a metachronous prostate cancer treated with conformal radiotherapy associated to 6 months of hormone therapy with luteinizing hormone/releasing hormone analog. During follow-up, prostate-specific antigen value increased to 0.27 ng/mL and the patient underwent 18F-methylcholine positron emission tomography/computed tomography (18F-choline PET/CT). The whole-body scan demonstrated a focus of increased uptake at level of the left cerebellopontine angle and at the left frontal lobe, corresponding to the known vestibular schwannoma and meningioma. A subsequent brain contrast-enhanced magnetic resonance imaging (MRI) showed an increased dimension of the left cerebellopontine neuroma and dimensional stability of the left frontal meningioma compared with previous MRI of 6 months earlier. To the best of our knowledge, we describe the first case of a 18F-choline PET/CT demonstrating a relapse of a vestibular schwannoma after stereotactic radiotherapy.http://www.wjnm.org/article.asp?issn=1450-1147;year=2019;volume=18;issue=2;spage=187;epage=188;aulast=Arico18F-Cholinepositron emission tomography/computed tomographyschwannoma
spellingShingle Demetrio Arico
Claudio Giardina
Carmelo Tuscano
Antonio Picone
Vincenzo Militano
First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy
World Journal of Nuclear Medicine
18F-Choline
positron emission tomography/computed tomography
schwannoma
title First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy
title_full First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy
title_fullStr First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy
title_full_unstemmed First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy
title_short First case of 18F-choline uptake in acoustic schwannoma after stereotactic radiotherapy
title_sort first case of 18f choline uptake in acoustic schwannoma after stereotactic radiotherapy
topic 18F-Choline
positron emission tomography/computed tomography
schwannoma
url http://www.wjnm.org/article.asp?issn=1450-1147;year=2019;volume=18;issue=2;spage=187;epage=188;aulast=Arico
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AT carmelotuscano firstcaseof18fcholineuptakeinacousticschwannomaafterstereotacticradiotherapy
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