Regulatory considerations for successful implementation of digital endpoints in clinical trials for drug development

Regulatory acceptance of Digital Health Technology (DHT) -derived endpoints can be a long, multifaceted and costly process. Success relies on establishing a global strategy as part of the development program including health authority consultations to ensure alignment with regulatory requirements. I...

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Bibliographic Details
Main Authors: Gül Erdemli, Tina Murphy, Sarah Walinsky
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01513-5
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Summary:Regulatory acceptance of Digital Health Technology (DHT) -derived endpoints can be a long, multifaceted and costly process. Success relies on establishing a global strategy as part of the development program including health authority consultations to ensure alignment with regulatory requirements. In this manuscript, the authors provide stepwise guidance for successful implementation of DHT-derived endpoints in clinical trials for drug development.
ISSN:2398-6352