A Reflux Linked GATA Factor Fulcrum Dictates Lineage Commitment Through GPRC5B During the Esophageal Dysplastic TransitionSummary
Background & Aims: GATA family transcription factors are somatically variable (SV) in esophageal adenocarcinomas (EAC) and inducible by simulated reflux. Our study examines the mechanisms whereby GATA family members (GATA4, GATA6, and the atypical TRPS-1) influence oncogenesis during the Bar...
Saved in:
| Main Authors: | Omar Abuhussein, Sara Hosseini-Farahabadi, Corina Stewart, Stephane Flibotte, Alireza Heravi-Moussavi, David Farnell, David Schaeffer, Fergal Donnellan, Frank McKeon, Wa Xian, Dermot Kelleher, Shane Patrick Duggan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Cellular and Molecular Gastroenterology and Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X25000931 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Progression to cancer in patients with confirmed dysplasia compared to dysplasia downgraded to non-dysplastic metaplasia in Barrett’s esophagus: a retrospective cohort study in Sweden
by: Peter Elbe, et al.
Published: (2024-11-01) -
Prevalencia del esófago de Barrett y características epidemiológicas de los pacientes
by: Yordanys Oliva Cosme, et al.
Published: (2022-03-01) -
Prevalence and clinical aspects of Barrett’s esophagus in Khakasia republic
by: N. N. Butorin, et al.
Published: (2010-11-01) -
Adenocarcinoma originating from long-segment Barrett's esophagus over 15 cm: a series of 3 cases
by: Naoki Kuwayama, et al.
Published: (2020-09-01) -
Barrett's Esophagus
by: Yong Kang Lee
Published: (2022-09-01)