Thermostable lamprey variable lymphocyte receptor antibody for detection of Plasmodium falciparum histidine rich protein-2
Abstract Lampreys use variable lymphocyte receptors (VLR) comprising leucine-rich-repeat (LRR) segments for antigen recognition, distinct from immunoglobulin-based receptors of jawed vertebrates. Lamprey VLRs are as diverse and antigen-specific as immunoglobulin-based antibodies, with unique advanta...
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| Main Authors: | Deepak Tomar, Balwan Singh, Masayuki Hirano, Samadhi Senanayake, Michael Aidoo, Eric Rogier, Oskar Laur, Brantley R. Herrin, Venkatachalam Udhayakumar |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-97790-x |
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