Viral hepatitis

The hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis. Acute viral hepatitis may be asymptomatic, with a rise in aminotransferase levels, it may be sym...

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Main Author: D. Brink
Format: Article
Language:English
Published: AOSIS 2006-09-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/666
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author D. Brink
author_facet D. Brink
author_sort D. Brink
collection DOAJ
description The hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis. Acute viral hepatitis may be asymptomatic, with a rise in aminotransferase levels, it may be symptomatic, with or without jaundice, or it may present as fulminant hepatitis. The hepatitis B (HBV), C (HCV) and D viruses are parenterally transmitted and can cause acute and chronic infections. When they persist in the chronic carrier state they may cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. The diagnosis of viral hepatitis in based on serology and molecular detection of the virus. There are no specific drug therapies available for patients with acute hepatitis A or hepatitis E infection, and management in based on symptomatic relief. Currently available treatments for chronic hepatitis B an C have limited efficacy, are expensive and may have severe side effects. Patients should be carefully selected and managed by a specialist with experience in this field. Vaccines are available for HAV and HBV.
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2078-6204
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series South African Family Practice
spelling doaj-art-bcad51cfef45443dbfb88100b18f5d672025-08-20T03:44:01ZengAOSISSouth African Family Practice2078-61902078-62042006-09-01488293510.1080/20786204.2006.10873442602Viral hepatitisD. Brink0Department of Medical Microbiology, University of Pretoria, South Africa; and, National Health Laboratory ServicesThe hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis. Acute viral hepatitis may be asymptomatic, with a rise in aminotransferase levels, it may be symptomatic, with or without jaundice, or it may present as fulminant hepatitis. The hepatitis B (HBV), C (HCV) and D viruses are parenterally transmitted and can cause acute and chronic infections. When they persist in the chronic carrier state they may cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. The diagnosis of viral hepatitis in based on serology and molecular detection of the virus. There are no specific drug therapies available for patients with acute hepatitis A or hepatitis E infection, and management in based on symptomatic relief. Currently available treatments for chronic hepatitis B an C have limited efficacy, are expensive and may have severe side effects. Patients should be carefully selected and managed by a specialist with experience in this field. Vaccines are available for HAV and HBV.https://safpj.co.za/index.php/safpj/article/view/666viral hepatitis
spellingShingle D. Brink
Viral hepatitis
South African Family Practice
viral hepatitis
title Viral hepatitis
title_full Viral hepatitis
title_fullStr Viral hepatitis
title_full_unstemmed Viral hepatitis
title_short Viral hepatitis
title_sort viral hepatitis
topic viral hepatitis
url https://safpj.co.za/index.php/safpj/article/view/666
work_keys_str_mv AT dbrink viralhepatitis