Efficacy and safety of radiotherapy combined with immunotherapy and targeted therapy versus immunotherapy plus targeted therapy alone in unresectable hepatocellular carcinoma: a retrospective study

Efficacy and safety of radiotherapy combined with immunotherapy and targeted therapy versus immunotherapy plus targeted therapy alone in unresectable hepatocellular carcinoma: a retrospective study

PurposeTo evaluate the efficacy and safety of radiotherapy combined with immunotherapy and targeted therapy (RT+IO+T) versus immunotherapy plus targeted therapy alone (IO+T) in patients with unresectable hepatocellular carcinoma (HCC). Given the limited prospective evidence supporting the integratio...

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Bibliographic Details
Main Authors: Yanling Yuan, Yongsheng Chen, Chumin Huang, Mindong Liu, Lihua Tong, Wubing Tang, Wen Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
immunotherapy
radiotherapy
targeted therapy
combination therapy
survival outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1643304/full
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