Insulin resistance as a systemic player in renal pathology: a review
Current review provides a multifaceted analysis of epidemiological, clinical and experimental evidence for insulin resistance as a systemic player in the development of renal pathology. We discuss both established and potential mechanisms for this effect. Aside from being a marker for glycemic disor...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2014-03-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/6313 |
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| _version_ | 1849729832835874816 |
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| author | Igor Adamovich Tyuzikov |
| author_facet | Igor Adamovich Tyuzikov |
| author_sort | Igor Adamovich Tyuzikov |
| collection | DOAJ |
| description | Current review provides a multifaceted analysis of epidemiological, clinical and experimental evidence for insulin resistance as a systemic player in the development of renal pathology. We discuss both established and potential mechanisms for this effect. Aside from being a marker for glycemic disorders, insulin resistance was shown to be an independent predictor of renal pathology, including such chronic conditions as urolithiasis, renal cysts and malignant renal neoplasms. Early detection and correction of insulin resistance is a promising approach to diagnostics, treatment and prevention of renal pathology. |
| format | Article |
| id | doaj-art-bca02f5c9dea43d693059e8d545ecb66 |
| institution | DOAJ |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2014-03-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-bca02f5c9dea43d693059e8d545ecb662025-08-20T03:09:04ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782014-03-01171475610.14341/DM2014147-566242Insulin resistance as a systemic player in renal pathology: a reviewIgor Adamovich Tyuzikov0Medical Centre for Diagnostics and Prevention «Plus», YaroslavlCurrent review provides a multifaceted analysis of epidemiological, clinical and experimental evidence for insulin resistance as a systemic player in the development of renal pathology. We discuss both established and potential mechanisms for this effect. Aside from being a marker for glycemic disorders, insulin resistance was shown to be an independent predictor of renal pathology, including such chronic conditions as urolithiasis, renal cysts and malignant renal neoplasms. Early detection and correction of insulin resistance is a promising approach to diagnostics, treatment and prevention of renal pathology.https://www.dia-endojournals.ru/jour/article/view/6313insulin resistancechronic kidney diseaseurolithiasisrenal cystsrenal cancerpathogenesisdiagnostics |
| spellingShingle | Igor Adamovich Tyuzikov Insulin resistance as a systemic player in renal pathology: a review Сахарный диабет insulin resistance chronic kidney disease urolithiasis renal cysts renal cancer pathogenesis diagnostics |
| title | Insulin resistance as a systemic player in renal pathology: a review |
| title_full | Insulin resistance as a systemic player in renal pathology: a review |
| title_fullStr | Insulin resistance as a systemic player in renal pathology: a review |
| title_full_unstemmed | Insulin resistance as a systemic player in renal pathology: a review |
| title_short | Insulin resistance as a systemic player in renal pathology: a review |
| title_sort | insulin resistance as a systemic player in renal pathology a review |
| topic | insulin resistance chronic kidney disease urolithiasis renal cysts renal cancer pathogenesis diagnostics |
| url | https://www.dia-endojournals.ru/jour/article/view/6313 |
| work_keys_str_mv | AT igoradamovichtyuzikov insulinresistanceasasystemicplayerinrenalpathologyareview |